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View Structure Prediction Details

Protein: daf-14
Organism: Caenorhabditis elegans
Length: 287 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for daf-14.

Description E-value Query
Range
Subject
Range
gi|1333645 - gi|1333645|gb|AAB39329.1| Mad2 gene product
386.0 [0..1] [287..179]

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Predicted Domain #1
Region A:
Residues: [1-287]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MYPDQVHLPA SINNPNMPIN DWLEDAPMPD CYNVPSTSTD ENNDPFPFSN ISSQSSLKPK  60
   61 TPEKAVVEVR PTGNEMLDPE PKYPKEEKPW CTIFYYELTV RLGKAFEAKV PTITIDGATG 120
  121 ASDECRMSLT SQPSSRNSKS SQIRNTVGAG IQLAYENGEL WLTVLTDQIV FVQCPFLNQT 180
  181 LNKPLKYVFR LQNKGDQKRM KIFDKEQFEQ EKTLALGPLT EKEVADERMR IFSNIRVSFC 240
  241 KGFGETYSRL KVVNLPCWIE IILHEPADEY DTVFRINNER PEIGSRS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 89.69897
Match: 1khxA
Description: Smad2 MH2 domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.11808492882744 bayes_pls_golite062009
protein binding 1.57677875769005 bayes_pls_golite062009
transforming growth factor beta receptor, cytoplasmic mediator activity 0.20688121694899 bayes_pls_golite062009
transmembrane receptor protein serine/threonine kinase signaling protein activity 0.17825540288715 bayes_pls_golite062009
signal transducer activity 0.15088578328411 bayes_pls_golite062009
molecular transducer activity 0.15088578328411 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle