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View Structure Prediction Details

Protein: wapl-1
Organism: Caenorhabditis elegans
Length: 748 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for wapl-1.

Description E-value Query
Range
Subject
Range
wapl-1 - status:Partially_confirmed UniProt:Q21843 protein_id:AAC48078.1
790.0 [0..1] [748..1]

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Predicted Domain #1
Region A:
Residues: [1-141]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSDANSDDP FSKPIVRKRF QATLAQQGIE DDQLPSVRSS DSPDVPDTPD VPVNQLSSPP  60
   61 LSLPETLSEG NAETLQNLSD DSEPEMLSQS STSSLNRRME DSAIDPSRGT RKSQSRGFDY 120
  121 DPAGERTTAP VQKKKKDEID M

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [142-748]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GGAKFFPKQE KKHVYTHKWT TEEDDEDEKT ISSSSNRYSS RPNQPAVSAR PRQPVYATTS  60
   61 TYSKPLASGY GSRVRHIKEA NELRESGEYD DFKQDLVYIL SSLQSSDASM KVKCLSAISL 120
  121 AKKCVSPDFR QFIKSENMTK SIVKALMDSP EDDLFALAAS TVLYLLTRDF NSIKIDFPSL 180
  181 RLVSQLLRIE KFEQRPEDKD KVVNMVWEVF NSYIEKQEVG GQKVSFDMRK ESLTPSSLII 240
  241 EALVFICSRS VNDDNLKSEL LNLGILQFVV AKIETNVNLI ADNADDTYSI LILNRCFRIL 300
  301 ESSSVFHKKN QAFLISHRSN ILISSLAKFL QVILDRVHQL AEEEVKKYIS CLALMCRLLI 360
  361 NISHDNELCC SKLGQIEGFL PNAITTFTYL APKFGKENSY DINVMMTSLL TNLVERCNAN 420
  421 RKVLIAQTVK MVIPGHDVEE VPALEAITRL FVYHESQAQI VDADLDRELA FDEGGCGDEE 480
  481 EEEEGGDESS DEDGVRKDGR LDRNKMDRMD QVDVVHALQQ VMNKASAHME GSVIASYHAL 540
  541 LVGFVLQQNE DHLDEVRKHL PGKNFQNMIS QLKRLYDFTK ATMAKRVESN SGFRAIERVI 600
  601 EYLERLE

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 0.985
Match: 1wa5B
Description: Crystal structure of the exportin Cse1p complexed with its cargo ( Kap60p) and RanGTP
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.4227425773296 bayes_pls_golite062009
protein binding 0.79300810988911 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle