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View Structure Prediction Details

Protein: egl-18
Organism: Caenorhabditis elegans
Length: 376 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for egl-18.

Description E-value Query
Range
Subject
Range
gi|38640803 - gi|38640803|gb|AAR26006.1| GATA transcription factor EGL-18A [Caenorhabditis elegans]
151.0 [0..1] [353..1]

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Predicted Domain #1
Region A:
Residues: [1-170]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSISIMTETR PESAEQQHHE VLQRPSDEPC SGCKQLQKDV AKTISMVMER MDKLQYRLDE  60
   61 LLKENNELKS SSVSSGKASP SPAESRSSPK LVETVVAPVS GARKRKPKER SPPAAASPLP 120
  121 DFSNLMNGFM FDPLNMSNPN GMMQLLSMVQ QQQQQQQHHQ HIENQQSVSP 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [171-261]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PQSKSVKIED PMDQDVKQEE SERSDIPTAT EAQNLLDALT AQFSSNGQAT STTSPPSSSS  60
   61 QVQAVIEAVA TPSSQSQDSS MFEKTETSGD P

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [262-376]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NAARCSNCRT DKTTAWRRDA EGKLVCNPCG LYYRLHKVRR PIEMRKNHIQ QRYRRKNKEK  60
   61 ESSAATQIFN QLLTQMPTMA TGGVSTDGAI NTFNLLEQIS QFTQAQELMN SSATF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 15.154902
Match: 2gatA
Description: Erythroid transcription factor GATA-1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.42599378647208 bayes_pls_golite062009
protein binding 0.576254539963841 bayes_pls_golite062009
transcription regulator activity 0.50063581643098 bayes_pls_golite062009
DNA binding 0.15755076348446 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle