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View Structure Prediction Details

Protein: CE27481
Organism: Caenorhabditis elegans
Length: 364 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE27481.

Description E-value Query
Range
Subject
Range
gi|73957135 - gi|73957135|ref|XP_863212.1| PREDICTED: similar to nin one binding protein isoform 2 [Canis familiar...
448.0 [0..8] [364..4]

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Predicted Domain #1
Region A:
Residues: [1-127]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTNKEKPIKH LVIDTCAIIA NRNLHALADH YYAPPQILDE LRSSAARKLW NTLPFEVTLR  60
   61 EPTQTALRAV IDASKTTGDF QSLSMVDIKM IALTYDLHRQ YVAENDVAET TEDDEKKNIE 120
  121 DLSAKVE

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.89
Match: 1o4wA
Description: Hypothetical protein AF0591
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
exonuclease activity 2.20884893250825 bayes_pls_golite062009
binding 1.86375021779651 bayes_pls_golite062009
exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 1.2490597933903 bayes_pls_golite062009
DNA binding 1.20124609530471 bayes_pls_golite062009
nucleic acid binding 1.09430328971825 bayes_pls_golite062009
3'-5' exonuclease activity 0.948612547993755 bayes_pls_golite062009
nuclease activity 0.932217848952722 bayes_pls_golite062009
endodeoxyribonuclease activity 0.620146212680627 bayes_pls_golite062009
deoxyribonuclease activity 0.536819960055588 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 0.457405908807867 bayes_pls_golite062009
protein binding 0.388252010955945 bayes_pls_golite062009
flap endonuclease activity 0.28412745918891 bayes_pls_golite062009
endonuclease activity 0.148170166509108 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [128-224]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QVTVGENTED TKEEEIEENE ESEDSAVSEG SESSESSESF DEDGWITQDN IEETLKKLGA  60
   61 FEIEENMLVG CLTTDFALQN VLLAMNLSLV SLSGYRI

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [225-364]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RKLKSFVLRC RTCFSTTSVM TKEFCPACGH KTLHKCAVSV DEDGNQQLHI NWNRMANRRG  60
   61 LVYTLANPKG GKHATNERLF EDQPMPHMRM AKIHMDPLAD GPFSVHDVTS RSAMLGVRTI 120
  121 NNRAKQNRNP NESKRGGRRK 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 25.0
Match: 2conA
Description: Solution Structure of RSGI RUH-035, a Zn-ribbon module in Mouse cDNA
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.07200237133183 bayes_pls_golite062009
RNA binding 1.94349729191855 bayes_pls_golite062009
protein binding 0.567759936480502 bayes_pls_golite062009
nucleic acid binding 0.493571954231014 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle