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View Structure Prediction Details

Protein: coh-4
Organism: Caenorhabditis elegans
Length: 609 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for coh-4.

Description E-value Query
Range
Subject
Range
coh-3 - status:Partially_confirmed UniProt:Q19232 protein_id:CAB01150.2
1016.0 [0..1] [609..1]

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Predicted Domain #1
Region A:
Residues: [1-192]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVISIDVPLK ASEEATVKFL LGIVFGSHKK LGLQSNRREC LRHDVLQASK LIHWILRNEK  60
   61 KNRRSLSVAC NLVYGNTIVL STQVARLLHD AIRARDIVAF TSYMAQEEER KRKTREQMEG 120
  121 DNSNKTPKKK RRQAEEFPLA PTPISVALRQ NITMPDVLSV HKNDQINVED DLAAPTMEQL 180
  181 EMMYGMLESE NR

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [193-316]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NTAIDLTFID RYSFNDARQN VHNLNLNMET DFQRPSDDFI RSQLMTPTKS IPQEEEVFQP  60
   61 ATHLKDVLRF AHLPIALDET ERRRSMDEEM EEARNSGINT EFLTPQQMNV PRIASEILEL 120
  121 DDEV

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [317-469]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LIPRTIPKAP HSATKNQMAE NEGAEEGINY KIPLRDMHHL MEDYSSLHFK DVEPLCRKTS  60
   61 KVMNLKDLLN PIPYYLRKGC NTDMWDLFKV KTRKFDSTIG RHDVSDTEDE DEEAERRNRR 120
  121 EAERELLETI DLSQMKFMAT PLKEKSPIMT PAH

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [470-609]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RPEEIEFREE LEVPRLEQFE PMNVNPISPR MDEPALLEEN WNSKPTWSNP ISENIADALT  60
   61 IRANIIHKLN SECPYEVTLD SIIPLAATSR REAARTFYTV LELLKEREIK AIQRDPYGNI 120
  121 DLLLSTDDIE DIDELAMADF 

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.61
Match: 1w1wE
Description: Sc Smc1hd:Scc1-C complex, ATPgS
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.683379929086364 bayes_pls_golite062009
transcription regulator activity 0.16959343932447 bayes_pls_golite062009
nucleic acid binding 0.0949481158963694 bayes_pls_golite062009
DNA binding 0.00746597740509714 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle