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View Structure Prediction Details

Protein: klc-2
Organism: Caenorhabditis elegans
Length: 522 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for klc-2.

Description E-value Query
Range
Subject
Range
gi|113476999, gi... - gi|113476999|ref|YP_723060.1| peptidase-like [Trichodesmium erythraeum IMS101], gi|110168047|gb|ABG5...
372.0 [0..3] [521..167]

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Predicted Domain #1
Region A:
Residues: [1-135]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNLAGSTIQA YRQRKIESLA KMSNMSQDDV TTGLRTVQQG LEALREEHST ISNTLETSVK  60
   61 GVKEDEAPLP KQKLSQINDN LDKLVCGVDE TSLMLMVFQL TQGMDAQHQK YQAQRRRLCQ 120
  121 ENAWLRDELS STQIK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 14.30103
Match: 2j9qA
Description: No description for 2j9qA was found.

Predicted Domain #2
Region A:
Residues: [136-522]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LQQSEQMVAQ LEEENKHLKY MASIKQFDDG TQSDTKTSVD VGPQPVTNET LQELGFGPED  60
   61 EEDMNASQFN QPTPANQMAA SANVGYEIPA RLRTLHNLVI QYASQGRYEV AVPLCKQALE 120
  121 DLEKTSGHDH PDVATMLNIL ALVYRDQNKY KEAANLLNEA LSIREKCLGE SHPAVAATLN 180
  181 NLAVLFGKRG KFKDAEPLCK RALEIREKVL GDDHPDVAKQ LNNLALLCQN QGKYEEVEKY 240
  241 YKRALEIYES KLGPDDPNVA KTKNNLSSAY LKQGKYKEAE ELYKQILTRA HEREFGQISG 300
  301 ENKPIWQIAE EREENKHKGE GATANEQAGW AKAAKVDSPT VTTTLKNLGA LYRRQGKYEA 360
  361 AETLEDVALR AKKQMSESRR MERSVMY

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 38.30103
Match: 1w3bA
Description: The superhelical TPR domain of O-linked GlcNAc transferase reveals structural similarities to importin alpha.
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.14253214573541 bayes_pls_golite062009
protein binding 1.65083457326273 bayes_pls_golite062009
signal sequence binding 0.49295886046194 bayes_pls_golite062009
peroxisome targeting sequence binding 0.0468412220974996 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle