YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: ced-9
Organism: Caenorhabditis elegans
Length: 280 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ced-9.

Description E-value Query
Range
Subject
Range
gi|25361752 - gi|25361752|pir||H88578 protein ced-9 [imported] - Caenorhabditis elegans
247.0 [0..20] [280..1]

Back

Predicted Domain #1
Region A:
Residues: [1-280]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTRCTADNSL TNPAYRRRTM ATGEMKEFLG IKGTEPTDFG INSDAQDLPS PSRQASTRRM  60
   61 SIGESIDGKI NDWEEPRLDI EGFVVDYFTH RIRQNGMEWF GAPGLPCGVQ PEHEMMRVMG 120
  121 TIFEKKHAEN FETFCEQLLA VPRISFSLYQ DVVRTVGNAQ TDQCPMSYGR LIGLISFGGF 180
  181 VAAKMMESVE LQGQVRNLFV YTSLFIKTRI RNNWKEHNRS WDDFMTLGKQ MKEDYERAEA 240
  241 EKVGRRKQNR RWSMIGAGVT AGAIGIVGVV VCGRMMFSLK 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 44.0
Match: 2a5yA
Description: Structure of a CED-4/CED-9 complex
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.68532136060219 bayes_pls_golite062009
protein binding 1.27467799975395 bayes_pls_golite062009
BH3 domain binding 0.73278409982916 bayes_pls_golite062009
protein dimerization activity 0.717110763227649 bayes_pls_golite062009
BH domain binding 0.513227895728431 bayes_pls_golite062009
protein heterodimerization activity 0.0857017957923898 bayes_pls_golite062009
caspase inhibitor activity 0.0810673056766702 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle