| Protein: | egl-10 |
| Organism: | Caenorhabditis elegans |
| Length: | 555 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for egl-10.
| Description | E-value | Query Range |
Subject Range |
|
|
468.0 | [0..6] | [545..1] |
|
Region A: Residues: [1-120] |
1 11 21 31 41 51
| | | | | |
1 MALPRLRVNA SNEERLVHPN HMVYRKMEML VNQMLDAEAG VPIKTVKSFL SKVPSVFTGQ 60
61 DLIGWIMKNL EMTDLSDALH LAHLIASHGY LFQIDDHVLT VKNDGTFYRF QTPYFWPSNC 120
121
|
| Detection Method: |  |
| Confidence: | 27.09691 |
| Match: | 1fshA |
| Description: | Segment polarity protein Dishevelled-1 |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| binding | 2.62737887048829 | bayes_pls_golite062009 |
| transcription regulator activity | 2.24995934604055 | bayes_pls_golite062009 |
| DNA binding | 1.98873150682164 | bayes_pls_golite062009 |
| nucleic acid binding | 1.88100667301756 | bayes_pls_golite062009 |
| transcription factor activity | 1.38071536959278 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 0.71352470280335 | bayes_pls_golite062009 |
| transcription activator activity | 0.637473513125737 | bayes_pls_golite062009 |
| protein binding | 0.498124455750984 | bayes_pls_golite062009 |
|
Region A: Residues: [121-206] |
1 11 21 31 41 51
| | | | | |
1 WDPENTDYAV YLCKRTMQNK AHLELEDFEA ENLAKLQKMF SRKWEFVFMQ AEAQYKVDKK 60
61 RDRQERQILD SQERAFWDVH RPVPGC
|
| Detection Method: | |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [207-314] |
1 11 21 31 41 51
| | | | | |
1 VNTTEVDFRK LSRSGRPKYS SGGHAALAAS TSGIGCTQYS QSVAAAHASL PSTSNGSATS 60
61 PRKNDQEPST SSGGESPSTS SAAAGTATTS APSTSTPPVT TITATINA
|
| Detection Method: | |
| Confidence: | 1.55 |
| Match: | 1xhmB |
| Description: | The Crystal Structure of a Biologically Active Peptide (SIGK) Bound to a G Protein Beta:Gamma Heterodimer |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| binding | 1.00364315876158 | bayes_pls_golite062009 |
| protein binding | 0.151788856727459 | bayes_pls_golite062009 |
| GTPase activity | 0.00398672503585712 | bayes_pls_golite062009 |
|
Region A: Residues: [315-555] |
1 11 21 31 41 51
| | | | | |
1 GSFRNNYYTR PGLRRCTQVQ DTLKLEIVQL NSRLSKNVLR TSKVVENYLA YYEQRRVFDP 60
61 LLTPPGSQAD PFQSQPNPWI NDTVDFWQHD KITGDIQTRR LKLWEDSFEE LLADSLGRET 120
121 LQKFLDKEYS GENLRFWWEV QKLRKCSSRM VPVMVTEIYN EFIDTNAATS PVNVDCKVME 180
181 VTEDNLKNPN RWSFDEAADH IYCLMKNDSY QRFLRSEIYK DLVLQSRKKV SLNCSFSIFA 240
241 S
|
| Detection Method: | |
| Confidence: | 37.09691 |
| Match: | 1agrE |
| Description: | Regulator of G-protein signalling 4, RGS4 |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| GTPase regulator activity | 1.63734012092956 | bayes_pls_golite062009 |
| nucleoside-triphosphatase regulator activity | 1.61106381835327 | bayes_pls_golite062009 |
| GTPase activator activity | 1.58095588540049 | bayes_pls_golite062009 |
| binding | 1.45102555794319 | bayes_pls_golite062009 |
| enzyme activator activity | 1.34819535045475 | bayes_pls_golite062009 |
| enzyme regulator activity | 1.22696878792766 | bayes_pls_golite062009 |
| protein binding | 1.09246587992573 | bayes_pls_golite062009 |
