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View Structure Prediction Details

Protein: lin-28
Organism: Caenorhabditis elegans
Length: 227 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for lin-28.

Description E-value Query
Range
Subject
Range
gi|37496491 - gi|37496491|emb|CAD48448.1| gag-pol fusion polyprotein precursor [Human immunodeficiency virus 1]
200.0 [0..46] [227..302]

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Predicted Domain #1
Region A:
Residues: [1-126]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSTVVSEGRN DGNNRYSPQD EVEDRLPDVV DNRLTENMRV PSFERLPSPT PRYFGSCKWF  60
   61 NVSKGYGFVI DDITGEDLFV HQSNLNMQGF RSLDEGERVS YYIQERSNGK GREAYAVSGE 120
  121 VEGQGL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 13.09691
Match: 1g6pA
Description: Major cold shock protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.99628257193121 bayes_pls_golite062009
nucleic acid binding 1.55535848952041 bayes_pls_golite062009
DNA binding 0.969246048450989 bayes_pls_golite062009
structure-specific DNA binding 0.890081297694346 bayes_pls_golite062009
single-stranded DNA binding 0.75578703467841 bayes_pls_golite062009
protein binding 0.0528188351789111 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [127-227]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KGSRIHPLGR KKAVSLRCFR CGKFATHKAK SCPNVKTDAK VCYTCGSEEH VSSICPERRR  60
   61 KHRPEQVAAE EAEAARMAAE KSSPTTSDDD IREKNSNSSD E

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 9.69897
Match: 1aafA
Description: NUCLEOCAPSID ZINC FINGERS DETECTED IN RETROVIRUSES: EXAFS STUDIES ON INTACT VIRUSES AND THE SOLUTION-STATE STRUCTURE OF THE NUCLEOCAPSID PROTEIN FROM HIV-1
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle