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View Structure Prediction Details

Protein: nhr-237
Organism: Caenorhabditis elegans
Length: 345 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for nhr-237.

Description E-value Query
Range
Subject
Range
gi|114627460 - gi|114627460|ref|XP_520345.2| PREDICTED: hypothetical protein [Pan troglodytes]
263.0 [0..6] [340..270]

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Predicted Domain #1
Region A:
Residues: [1-73]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEIPTPHQIC RVCGECADAV HFGALSCRAC AAFFRRKVAA GKPLSSSRCS GSCKLENQVL  60
   61 RRLCAKCRYE KCV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 15.69897
Match: 2hanB
Description: No description for 2hanB was found.

Predicted functions:

Term Confidence Notes
binding 1.18770607371139 bayes_pls_golite062009
protein binding 0.699012253331291 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [74-345]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QVGMRTSAVL SRLAVKSEPE FESLLDQIKL AYERLQMARK EAFHTEGHIP KMIKYQEMHK  60
   61 MCSFDLQLVS QHFTSIFQSL TPISEAQKVT LGEYFTVPFV LLDGSYRSVE SDYIVFPNGD 120
  121 YVDAQNIDAF YQNPDEKDES IGSSVASILE PYWRLHHQTL WEQMKKVKPS LIEFLVLSAF 180
  181 IFWDFGLQGQ SEECIKVCNQ LRARVNAELS TYEKTFYTAG DYSLRVAEVV YLLQSVQKSL 240
  241 AIMHSCKTLG YVFDFRDRTC PLNDNLEKTH SK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 42.69897
Match: 1lbdA
Description: LIGAND-BINDING DOMAIN OF THE HUMAN NUCLEAR RECEPTOR RXR-ALPHA
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.07679393058916 bayes_pls_golite062009
protein binding 1.4692467191721 bayes_pls_golite062009
ligand-dependent nuclear receptor activity 1.46824905227088 bayes_pls_golite062009
transcription regulator activity 1.44313615088064 bayes_pls_golite062009
receptor activity 1.27827487658808 bayes_pls_golite062009
DNA binding 1.07558579137079 bayes_pls_golite062009
nucleic acid binding 0.885522697705667 bayes_pls_golite062009
signal transducer activity 0.875578759851886 bayes_pls_golite062009
molecular transducer activity 0.875578759851886 bayes_pls_golite062009
transcription factor activity 0.58279231726985 bayes_pls_golite062009
sequence-specific DNA binding 0.25945001118854 bayes_pls_golite062009
transcription activator activity 0.15629984940944 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle