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View Structure Prediction Details

Protein: klc-1
Organism: Caenorhabditis elegans
Length: 516 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for klc-1.

Description E-value Query
Range
Subject
Range
gi|113476999, gi... - gi|113476999|ref|YP_723060.1| peptidase-like [Trichodesmium erythraeum IMS101], gi|110168047|gb|ABG5...
382.0 [0..4] [514..197]

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Predicted Domain #1
Region A:
Residues: [1-89]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVISLGDDIT TVLKTVQQTL FALRDEHEAA TRILEANLIN SDSSEPSLPS EKMGLIDESL  60
   61 GKVMDGGDEA SLLIMMDKLM QSYDVQLSK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 5.0
Match: 1xnfA
Description: Crystal structure of E.coli TPR-protein NlpI
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [90-516]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NHESIRLLRQ ENTWLLDELT TTQRKLQESE RTVAHLEEER DHYKFQDSMN YLNSDFQHTT  60
   61 SVDATPMMVD TLQELGFGPE EEDQNNNQAD QGCRSSSFSN PISNDYQLPT RLQTLQNLVI 120
  121 QYMEQGRFEV AIPLCKQALE DVVKVHGNVH LDVATMLNVL AIVYRNQENF KDAAIYLEKA 180
  181 LSIRVQCCGE NHHSVAATLN NLAIAYGKRG KYKESEPLCK RALEIRKNLL GPNHPDVAKQ 240
  241 LTNLGIVTQQ LEKYEETENY FKQALSIYNR AFPENHQNVI KTKNQLASVF LKQGKYQEAE 300
  301 EMYKNILSKV AITGNKPIWR IAEDREERQR NGIPKVDDES FNVNPTTVMD SNVMSTIKNL 360
  361 AAVYRKQGKE EAAGTLEEAL GAKKQINGGA DHTNSTASSV ETSSAVAINP AQSGIKKRIM 420
  421 HFVGLNF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 44.522879
Match: 1w3bA
Description: The superhelical TPR domain of O-linked GlcNAc transferase reveals structural similarities to importin alpha.
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.14253214573541 bayes_pls_golite062009
protein binding 1.65083457326273 bayes_pls_golite062009
signal sequence binding 0.49295886046194 bayes_pls_golite062009
peroxisome targeting sequence binding 0.0468412220974996 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle