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View Structure Prediction Details

Protein: unc-11
Organism: Caenorhabditis elegans
Length: 586 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for unc-11.

Description E-value Query
Range
Subject
Range
unc-11 - status:Confirmed UniProt:Q9XZI6 protein_id:AAK68216.1
407.0 [0..1] [368..1]

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Predicted Domain #1
Region A:
Residues: [1-325]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQTIEKALHQ PMPFTTGGQT ISDRLTAAKH SLAGSQLGKT ICKATTEEVM APKKKHLDYL  60
   61 LHCTNEPNVS IPSMANLLIE RTQNPNWTVV YKALITIHNI MCYGNERFSQ YLASCNTTFN 120
  121 LTAFVDKVGG AGGYDMSTHV RRYAKYIGEK INTYRMCAFD FCKVKRGRED GLLRTMHTDK 180
  181 LLKTIPILQN QIDALLEFSV TTSELNNGVI NCSFILLFRD LIRLFACYND GIINVLEKYF 240
  241 DMNKKQCRDA LDTYKSFLTR LDKVAEFLRV AESVGIDRGE IPDLTRAPAS LLEALEAHLI 300
  301 HLEGGKAPPP TQQHVAPHQF TTGFA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 104.0
Match: 1hf8A
Description: Clathrin assembly lymphoid myeloid leukaemia protein, Calm
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
clathrin binding 3.05300014576459 bayes_pls_golite062009
binding 2.13445840178249 bayes_pls_golite062009
protein binding 1.7891964555817 bayes_pls_golite062009
phospholipid binding 1.38798066582556 bayes_pls_golite062009
phosphoinositide binding 1.26458267960741 bayes_pls_golite062009
lipid binding 0.4499495998145 bayes_pls_golite062009
protein domain specific binding 0.14699617064037 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [326-400]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FSQQPQPALG DAERQRYIEL EQERLRQFED QKKSINSANP FANDVASAAP APATSAAQPD  60
   61 LLDMFQSSAA PAPQT

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [401-586]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ADVTNPFGNF AAPSAFPTNV PPPAAHSAPF GVQPAPQHSA APFYANLHQA PPMQSQAPNG  60
   61 HQAAPFGYPN AHPDDLARMT AQMSLNQQGA PAGWNTTTSA VSNNPFGATS APQPMYTAPM 120
  121 GMYQQPFGAQ PMWNPAMAAY GQQYGYGQPV PPQQQHQIQL VHAAMAAKNA AQAQQAQAAS 180
  181 ADPFGL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 7.69897
Match: 1m2vB
Description: Sec24
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle