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View Structure Prediction Details

Protein: cdt-1
Organism: Caenorhabditis elegans
Length: 684 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for cdt-1.

Description E-value Query
Range
Subject
Range
gi|70878483 - gi|70878483|gb|EAN91735.1| trans-sialidase, putative [Trypanosoma cruzi]
gi|71649745 - gi|71649745|ref|XP_813586.1| trans-sialidase [Trypanosoma cruzi strain CL Brener]
323.0 [0..2] [680..752]

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Predicted Domain #1
Region A:
Residues: [1-183]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSRVTRSRS QTPQTAVTDF FKTTRKPRAR GEKKIIDESI TKTTTIKEVQ IPAAPIVENK  60
   61 SSRTRARTPS RQAELSSSGT PPKKAREAEA EAPELPKIHE DIILENPAPQ KSAIDKLMEA 120
  121 SGPAKKKAGI RTVADLQARI AAKGAAKAIH EQNLKNKTKQ VDDHVELLKS PKKPVIVEHH 180
  181 KSP

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [184-525]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QKSKAARNLF SPKKPVPDYI IPGFNVLKSA EKVRGEQDDA HEEEGKRMTA EFLKSSRLID  60
   61 EVKESARQRI ELPTAYEHLA DTFKRIDQIT AIFIGQNRSC VVPELIKNVK NTSGKDFSNE 120
  121 HLSQILHVYP QSYHIEMREQ RKAFGQGGKY ELEVRPNLVE DLRGYIYEKS PTDGDTEDLP 180
  181 LVCPSKLLSP KKSPRKQVQP ALRKPEVDGR IRLDAARQRD RAHVFRYKLA SIVTKCHTEF 240
  241 LESQGLCASS NIKRMHPLFR LDKHCPSLPQ VKLPEPPLQK SSIHIGMKEA LDKYMDQVSL 300
  301 PSFVQKAYQD LKSPLKSTTG ASGTVPISPK KFSEMQKEQK SQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 10.69897
Match: 1wlqC
Description: Strucure of Geminin-Cdt1 complex
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.835523092977445 bayes_pls_golite062009
transcription regulator activity 0.4843036104266 bayes_pls_golite062009
nucleic acid binding 0.37117756729668 bayes_pls_golite062009
DNA binding 0.3118855114645 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [526-684]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GAMSLLERIR AKEAIKKAAE ACIDKDLERR KQRLTLLRDR YVRIVCNHYT AKRAQTMEID  60
   61 VICKFVQFSS SNSSSIPDIM DHLRLLCEVA PMYISEASLM NKKYFRFTDN NIEAINELLD 120
  121 EELQITQKKI DEQRNTQIAQ MSHHHTPRPS KAARSLKFH

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle