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View Structure Prediction Details

Protein: CE20875
Organism: Caenorhabditis elegans
Length: 622 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE20875.

Description E-value Query
Range
Subject
Range
gi|157762450 - gi|157762450|ref|XP_001673567.1| Hypothetical protein CBG23435 [Caenorhabditis briggsae AF16]
gi|39592220, gi|... - gi|39592220|emb|CAE75441.1| Hypothetical protein CBG23435 [Caenorhabditis briggsae], gi|187021011|em...
402.0 [0..1] [614..1]

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Predicted Domain #1
Region A:
Residues: [1-79]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTNDVEMKSE TEELPPFPTV HILQVVKDAQ QQHGLRHGDY ARYRKYCAAK LERMRKALKF  60
   61 TNSHNCQKKR KAKFVKKWL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [80-521]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SVESVQNVQF LNFGIFESER RYAEAMIDKI TLEDNPEKSR KKFSMINSLR KAVLHATNLE  60
   61 KIVQESERFD APTKLEAQAY AAWMRGMCSF ESRNWQKASE SLKLAKTVYE KLAEATNNTT 120
  121 LSSIFKGRCR EIQPQLRLCE FNIAESPGAV GTMTELMELR MQMGEGGDSS VDKLISEMRA 180
  181 SATSAEVVTI EWGGAKSTVD DEKAKQVVQE WKQTEVELAQ CQTPKEKMAL FEKATADTRD 240
  241 AIDRISDIIR RKSSENADTT VLQSIKAYLE FLKMNGTASR YLAIIDNTKS EKKSKPQDLL 300
  301 RLYDSVIEIY KEVAEIPGAD HDKNLIQAFE VKVEYYRAFR CFYMASSYSA LHKYSEAAAL 360
  361 FDRTVSRVQD AEGKLKKLKS SSFITNETQS SLNELRSEVE SAKVTVRAAR LASAAGDVKT 420
  421 DSELAKIIDK RPLLETVNEW RQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 33.154902
Match: 1w3bA
Description: The superhelical TPR domain of O-linked GlcNAc transferase reveals structural similarities to importin alpha.
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
signal sequence binding 6.43572978129744 bayes_pls_golite062009
binding 2.52126334054344 bayes_pls_golite062009
protein binding 1.52807685989528 bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH, with oxygen as acceptor 0.534990536504941 bayes_pls_golite062009
peroxisome targeting sequence binding 0.473199490747666 bayes_pls_golite062009
transcription regulator activity 0.420068756437132 bayes_pls_golite062009
DNA binding 0.17110069978022 bayes_pls_golite062009
nucleic acid binding 0.16224979197079 bayes_pls_golite062009
RNA binding 0.139792032742725 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [522-622]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 WDVRNSLKDK KTIPVASLPP AFIPMPNKPI FFDLANFHLT MPNVDDRLEK LQKDRDATPK  60
   61 KAAKGSSAAA ASSKTSNQEE EEQQGLTGML SGWKKSFWGN K

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle