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View Structure Prediction Details

Protein: unc-60
Organism: Caenorhabditis elegans
Length: 165 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for unc-60.

Description E-value Query
Range		 Subject
Range
gi|48374972 - gi|48374972|gb|AAT42170.1| putative actin depolymerizing factor [Sorghum bicolor]
 168.0 [0..2] [158..329]
gi|84028521 - gi|84028521|gb|ABC49719.1| actin depolymerizing factor-like protein [Arachis hypogaea]
 161.0 [0..2] [159..5]
unc-60 - actin depolymerizing factor status:Confirmed UniProt:Q07750 protein_id:AAL02462.2
 160.0 [0..1] [155..1]
ADF1_ARATH - Actin-depolymerizing factor 1 OS=Arabidopsis thaliana GN=ADF1 PE=1 SV=1
gi|195604826 - gi|195604826|gb|ACG24243.1| hypothetical protein [Zea mays]
 158.0 [0..2] [159..5]
ADF2_PETHY - Actin-depolymerizing factor 2 OS=Petunia hybrida GN=ADF2 PE=2 SV=1
 157.0 [0..2] [160..5]
gi|109105452 - gi|109105452|ref|XP_001118077.1| PREDICTED: similar to Cofilin-1 (Cofilin, non-muscle isoform) (18 k...
 156.0 [0..2] [162..290]
gi|106879609 - gi|106879609|emb|CAJ38388.1| actin-depolymerizing factor [Plantago major]
 156.0 [0..3] [159..6]

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Predicted Domain #1
Region A:
Residues: [1-165] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSGVMVDPD VQTSFQKLSE GRKEYRYIIF KIDENKVIVE AAVTQDQLGI TGDDYDDSSK  60
   61 AAFDKFVEDV KSRTDNLTDC RYAVFDFKFT CSRVGAGTSK MDKIIFLQIC PDGASIKKKM 120
  121 VYASSAAAIK TSLGTGKILQ FQVSDESEMS HKELLNKLGE KYGDH

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 39.221849
Match: 1f7sA
Description: Cofilin (actin depolymerizing factor, ADF)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
actin binding 7.52071741004022 bayes_pls_golite062009
cytoskeletal protein binding 6.04859625643932 bayes_pls_golite062009
actin filament binding 5.45532510538573 bayes_pls_golite062009
binding 2.84811181543046 bayes_pls_golite062009
protein binding 1.87981807141519 bayes_pls_golite062009
phosphatidylinositol-4,5-bisphosphate binding 1.3406661967545 bayes_pls_golite062009
phosphatidylserine binding 0.588992286163708 bayes_pls_golite062009
structural constituent of cytoskeleton 0.482954032096802 bayes_pls_golite062009
actin monomer binding 0.224304003054399 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle