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View Structure Prediction Details

Protein: CE20297
Organism: Caenorhabditis elegans
Length: 404 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE20297.

Description E-value Query
Range
Subject
Range
gi|149021017, gi... - ref|XP_341555.1| similar to Kin protein [Rattus norvegicus], gi|157817336|ref|NP_001102999.1| antige...
441.0 [0..1] [404..1]

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Predicted Domain #1
Region A:
Residues: [1-60]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGKHEKGSSK DLANRTKSKG LQKLKFFCQM CQKQCRDANG FKCHLTSEAH QRQLLLFAEN  60
   61 

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.25
Match: 1zu1A
Description: Solution Structure of the N-terminal Zinc Fingers of the Xenopus laevis double stranded RNA binding protein ZFa
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
nucleic acid binding 3.3313734687716 bayes_pls_golite062009
DNA binding 3.15523680513517 bayes_pls_golite062009
transcription regulator activity 3.13450410278168 bayes_pls_golite062009
binding 2.79894364685962 bayes_pls_golite062009
transcription factor activity 2.20435466497656 bayes_pls_golite062009
structure-specific DNA binding 1.75169697620651 bayes_pls_golite062009
double-stranded DNA binding 1.44934603674695 bayes_pls_golite062009
RNA polymerase II transcription factor activity 1.39128012329158 bayes_pls_golite062009
transcription activator activity 1.29160378137114 bayes_pls_golite062009
protein binding 0.852654490075478 bayes_pls_golite062009
transcription repressor activity 0.772384703325109 bayes_pls_golite062009
sequence-specific DNA binding 0.628218277487796 bayes_pls_golite062009
transcription factor binding 0.565898381175308 bayes_pls_golite062009
chromatin binding 0.530600410029043 bayes_pls_golite062009
catalytic activity 0.263007611601737 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 0.0453997626048568 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [61-134]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SNSYLRQFSN DFEKNFMQLL RTSYGTKRVR ANEVYNAFIK DKGHVHMNST VWHSLTGFVQ  60
   61 YLGSSGKCKI DEGD

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [135-347]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KGWYIAYIDQ EALIRKEEDQ RKQQQEKDDE ERHMQIMDGM VQRGKELAGD DEHEYEATEL  60
   61 IRDTPDQKIQ LDLNLGILDR KLDVKSGVAS AKISIFDMPK VKKEDPDEPG PSQPSRKSGK 120
  121 KRSRSRSPAA KKFSKKSALD EIKEMEERKK ERKNRKDYWM REGIVVKVIT KSLGSEYYKA 180
  181 KGVVRKVVDD YTAQVKLDDG TVVKLDQEHV ETV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 4.154902
Match: 1i84S
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [348-404]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IPSLGRQMMI VNGAYRGQEA TLESIDEKRF SLRLKIASGP TRGRQIDVPY EDASKLA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 29.522879
Match: 2ckkA
Description: No description for 2ckkA was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle