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View Structure Prediction Details

Protein: nhr-85
Organism: Caenorhabditis elegans
Length: 336 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for nhr-85.

Description E-value Query
Range
Subject
Range
gi|114627460 - gi|114627460|ref|XP_520345.2| PREDICTED: hypothetical protein [Pan troglodytes]
220.0 [0..1] [248..339]

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Predicted Domain #1
Region A:
Residues: [1-336]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSRDAVRFGR VPKREKARMF EEMQKTNVQS QRDQIAIQYE NLTEVMHKIN QAFGTLQATL  60
   61 EKCTGPIYTD RCPITSNFIV IPLKAAIDFA NSIPAFLSIT QTQRVHLLQN SVFDVMLLAS 120
  121 ASASTSQHFP PGGLTYDQSS ANPIIPQAIQ SISARIRQLP PQTVPILTAI AVCQADLLPE 180
  181 SQQPMLLAER LWCVLGKLGG IQSLATAPSL LADVRTLRQW HSDRLRQMSQ ISQHFSQNLL 240
  241 IAPVAAAAPV LLPPAFLSPP ASATSTSSSS VKSEFIERHP SIASLLERPR RISSSGAQEP 300
  301 LNLSLPHVRH QVKRDVDSDE QLEEMKVSPV PTTLSE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 47.69897
Match: 1xdkB
Description: Crystal Structure of the RARbeta/RXRalpha Ligand Binding Domain Heterodimer in Complex with 9-cis Retinoic Acid and a Fragment of the TRAP220 Coactivator
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.15996699473685 bayes_pls_golite062009
transcription regulator activity 0.46162010671465 bayes_pls_golite062009
protein binding 0.33427459029264 bayes_pls_golite062009
nucleic acid binding 0.15459949087509 bayes_pls_golite062009
DNA binding 0.14395376162921 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle