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View Structure Prediction Details

Protein: ape-1
Organism: Caenorhabditis elegans
Length: 769 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ape-1.

Description E-value Query
Range
Subject
Range
gi|115970347 - gi|115970347|ref|XP_001193670.1| PREDICTED: similar to ankyrin 2,3/unc44, partial [Strongylocentrotu...
700.0 [0..3] [768..233]

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Predicted Domain #1
Region A:
Residues: [1-166]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVTTSSGGGI GYPANNGVTQ VSLIHSSDSV RTVSTAPIYR PTSSMASTMA HKSSTAPFIS  60
   61 ANQRMSKPPV RVVAQPPPPH PQALSQQYHQ QNPMMMYSAP NTRPHVIPTM QVQPTMAAQI 120
  121 KRNNPVNAQF QNPSEMIADY GVKPQSVEMV QRVRAVRRQV ADEETE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [167-284]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LRRLRELEHE TAQLQNKNYG RERELNVQGS MLKEAQLELR NASMRAQSLN KHLEEMYRRR  60
   61 QTAAAAALVE QRKMQQHQIL LARAANQVST QEVIRPRASV EPFQVNNTQQ QQPSPQMM

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [285-348]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KSEEFSEKRD LNGQTGSYDA IDGSGDHQKI PTEPSYLAPC KENQQKYSEL SKMASTDPHS  60
   61 NHSS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [349-643]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PSTSSQKAPT LITFSPPSFE QKINSSTMTR DSPFVERPTS FGDSLDESRL RSGKTDLVSL  60
   61 RSDSLKATKR RSWAASEGTS MSEAEMIHRL LDEQRRGRSH FIPQLPTSQE EPSAITSETY 120
  121 AEEVVNSESK QVATSSDSTN NLELPTEQMV LGSDTTTEED ASSCSTRSDD GQNLEMEVAI 180
  181 ERRTVKGILR RPNEKMNKGR IEFDPLALLL DAALEGELDL VRSSASKLTD VSQANDEGIT 240
  241 ALHNAICAGH YEIVRFLIEN DADVNAQDSD GWTPLHCAAS CNNLPMVRQL VEGGG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 27.69897
Match: 1k3zD
Description: Transcription factor inhibitor I-kappa-B-beta, IKBB
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
protein binding 1.85450951074782 bayes_pls_golite062009
binding 1.67882758018256 bayes_pls_golite062009

Predicted Domain #5
Region A:
Residues: [644-769]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 CVLASTLSDM ETPVEKCEED EDGYDGCLKY LSAAHNSTGS INTGKVYAAY GYEAAFEDEL  60
   61 SFDAGDELTV IEKDKVDKNW WTCEKNNGEK GQVPRTYLAL YPSLKYRKKL NFVMFDLPLE 120
  121 SNNNVE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 32.39794
Match: 1ycsB
Description: 53BP2
Matching Structure (courtesy of the PDB):

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