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View Structure Prediction Details

Protein: asp-3
Organism: Caenorhabditis elegans
Length: 398 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for asp-3.

Description E-value Query
Range
Subject
Range
gi|118344558, gi... - gi|55771082|dbj|BAD69801.1| cathepsin D1 [Takifugu rubripes], gi|118344558|ref|NP_001072052.1| cathe...
357.0 [0..1] [395..1]

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Predicted Domain #1
Region A:
Residues: [1-398]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSGRVFLLLA LVALASAIQR IKLEKRTYTR EQYKFGSIQE HLKAKYVPGY IPNKDAFNEG  60
   61 LSDYSNAQYY GPVTIGTPPQ NFQVLFDTGS SNLWVPCANC PFGDIACRMH NRFDCKKSSS 120
  121 CTATGASFEI QYGTGSMKGT VDNDVVCFGH DTTYCTDKNQ GLACATSEPG ITFVAAKFDG 180
  181 IFGMGWDTIS VNKISQPMDQ IFANSAICKN QLFAFWLSRD ANDITNGGEI TLCETDPNHY 240
  241 VGNIAWEPLV SEDYWRIKLA SVVIDGTTYT SGPIDSIVDT GTSLLTGPTD VIKKIQHKIG 300
  301 GIPLFNGEYE VECSKIPSLP NITFNLGGQN FDLQGKDYIL QMSNGNGGST CLSGFMGMDI 360
  361 PAPAGPLWIL GDVFIGRFYS VFDHGNKRVG FATSRTGK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 84.69897
Match: 2psgA
Description: REFINED STRUCTURE OF PORCINE PEPSINOGEN AT 1.8 ANGSTROMS RESOLUTION
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
aspartic-type endopeptidase activity 7.9145950161796 bayes_pls_golite062009
aspartic-type peptidase activity 7.9145950161796 bayes_pls_golite062009
peptidase activity 5.78181196721293 bayes_pls_golite062009
endopeptidase activity 5.4888481808613 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 5.39972232367526 bayes_pls_golite062009
hydrolase activity 4.34796304893506 bayes_pls_golite062009
catalytic activity 1.54514410489082 bayes_pls_golite062009
binding 0.902062095182608 bayes_pls_golite062009
receptor binding 0.561225023505917 bayes_pls_golite062009
protein binding 0.094081389440774 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle