YRC Public Data Repository - Protein Structure Prediction

Protein:	CE19170
Organism:	Caenorhabditis elegans
Length:	294 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE19170.

Description	E-value	Query Range	Subject Range
gi\|48859745, gi\|... - gi\|67874591\|ref\|ZP_00504301.1\| RNA methyltransferase TrmH, group 3 [Clostridium thermocellum ATCC 27... gi\|196197583, gi... - gi\|196253021\|ref\|ZP_03151665.1\| RNA methyltransferase, TrmH family, group 3 [Clostridium thermocellu...	227.0	[0..13]	[291..1]
gi\|45512742 - ref\|ZP_00164308.1\| COG0566: rRNA methylases [Synechococcus elongatus PCC 7942] gi\|56750360, gi\|... - gi\|56750360\|ref\|YP_171061.1\| tRNA/rRNA methyltransferase [Synechococcus elongatus PCC 6301], gi\|5668...	222.0	[0..16]	[293..2]
gi\|25316695 - pir\|\|A83664 tRNA/rRNA methyltransferase BH0113 [imported] - Bacillus halodurans (strain C-125) gi\|15612676, gi\|... - gi\|15612676\|ref\|NP_240979.1\| tRNA/rRNA methyltransferase [Bacillus halodurans C-125], gi\|10172725\|db...	221.0	[0..40]	[291..1]
gi\|75907658, gi\|... - gi\|75907658\|ref\|YP_321954.1\| tRNA/rRNA methyltransferase (SpoU) [Anabaena variabilis ATCC 29413], gi...	220.0	[0..16]	[293..2]
gi\|114770938 - gi\|114770938\|ref\|ZP_01448406.1\| hypothetical protein OM2255_16034 [alpha proteobacterium HTCC2255] gi\|221133725 - gi\|221133725\|ref\|ZP_03560030.1\| 23S rRNA (guanosine-2'-O-)-methyltransferase [Glaciecola sp. HTCC299... gi\|114770938, gi... - gi\|114770938\|ref\|ZP_01448406.1\| hypothetical protein OM2255_16034 [alpha proteobacterium HTCC2255], ...	218.0	[0..39]	[292..2]
gi\|48825603 - ref\|ZP_00286846.1\| COG0566: rRNA methylases [Enterococcus faecium] gi\|69245491, gi\|... - gi\|69245491\|ref\|ZP_00603455.1\| RNA methyltransferase TrmH, group 3 [Enterococcus faecium DO], gi\|681...	217.0	[0..2]	[292..9]
gi\|48892550, gi\|... - gi\|71674113\|ref\|ZP_00671860.1\| RNA methyltransferase TrmH, group 3 [Trichodesmium erythraeum IMS101]...	216.0	[0..12]	[293..4]
gi\|7469455 - pir\|\|S76163 hypothetical protein - Synechocystis sp. (strain PCC 6803) Y955_SYNY3 - Uncharacterized tRNA/rRNA methyltransferase slr0955 OS=Synechocystis sp. (strain ATCC 27184 / PCC 68... Y955_SYNY3 - Uncharacterized tRNA/rRNA methyltransferase slr0955 OS=Synechocystis sp. (strain PCC 6803 / Kazusa) ...	216.0	[0..3]	[293..84]
gi\|62130448, gi\|... - gi\|62182815\|ref\|YP_219232.1\| 23S rRNA (guanosine-2'-O-)-methyltransferase [Salmonella enterica subsp... gi\|56416160, gi\|... - gi\|56416160\|ref\|YP_153235.1\| 23S rRNA (guanosine-2'-O-)-methyltransferase [Salmonella enterica subsp... gi\|238910527 - gi\|238910527\|ref\|ZP_04654364.1\| 23S rRNA (guanosine-2'-O-)-methyltransferase [Salmonella enterica su... RLMB_SALTY - 23S rRNA (guanosine-2'-O-)-methyltransferase RlmB OS=Salmonella typhimurium (strain LT2 / SGSC1412 /... lcl\|NC_016856.1_... - [gene=yjfH] [protein=23S rRNA (guanosine-2'-O-)-methyltransferase] [protein_id=YP_005240682.1] [loca... gi\|197365085, gi... - gi\|197365085\|ref\|YP_002144722.1\| 23S rRNA (guanosine-2'-O-)-methyltransferase [Salmonella enterica s... gi\|204927331, gi... - gi\|204927331\|ref\|ZP_03218533.1\| RNA methyltransferase, TrmH family, group 3 [Salmonella enterica sub... gi\|213428664 - gi\|213428664\|ref\|ZP_03361414.1\| 23S rRNA (guanosine-2'-O-)-methyltransferase [Salmonella enterica su... gi\|213582911 - gi\|213582911\|ref\|ZP_03364737.1\| 23S rRNA (guanosine-2'-O-)-methyltransferase [Salmonella enterica su... gi\|194449058, gi... - gi\|194449058\|ref\|YP_002048412.1\| 23S rRNA (guanosine-2'-O-)-methyltransferase [Salmonella enterica s... gi\|194469123, gi... - gi\|194469123\|ref\|ZP_03075107.1\| RNA methyltransferase, TrmH family, group 3 [Salmonella enterica sub... RLMB_SALTY - 23S rRNA (guanosine-2'-O-)-methyltransferase rlmB OS=Salmonella typhimurium GN=rlmB PE=3 SV=1 gi\|194734163, gi... - gi\|194734163\|ref\|YP_002117310.1\| RNA methyltransferase, TrmH family, group 3 [Salmonella enterica su... gi\|197263055, gi... - gi\|197263055\|ref\|ZP_03163129.1\| RNA methyltransferase, TrmH family, group 3 [Salmonella enterica sub... gi\|197287651, gi... - gi\|197287651\|gb\|EDY27042.1\| RNA methyltransferase, TrmH family, group 3 [Salmonella enterica subsp. ... gi\|205336077, gi... - gi\|205336077\|gb\|EDZ22841.1\| RNA methyltransferase, TrmH family, group 3 [Salmonella enterica subsp. ... gi\|205341078, gi... - gi\|205341078\|gb\|EDZ27842.1\| RNA methyltransferase, TrmH family, group 3 [Salmonella enterica subsp. ... gi\|194444737, gi... - gi\|194444737\|ref\|YP_002043624.1\| RNA methyltransferase, TrmH family, group 3 [Salmonella enterica su... gi\|161617640, gi... - gi\|161617640\|ref\|YP_001591605.1\| 23S rRNA (guanosine-2'-O-)-methyltransferase [Salmonella enterica s... gi\|205327237, gi... - gi\|205327237\|gb\|EDZ14001.1\| RNA methyltransferase, TrmH family, group 3 [Salmonella enterica subsp. ... RLMB_SALTY - 23S rRNA (guanosine-2'-O-)-methyltransferase RlmB OS=Salmonella typhimurium GN=rlmB PE=3 SV=1 gi\|168231407, gi... - gi\|205334208\|gb\|EDZ20972.1\| RNA methyltransferase, TrmH family, group 3 [Salmonella enterica subsp. ... gi\|213852966 - gi\|213852966\|ref\|ZP_03382498.1\| 23S rRNA (guanosine-2'-O-)-methyltransferase [Salmonella enterica su... gi\|214003352 - gi\|214003352\|ref\|ZP_03414087.1\| 23S rRNA (guanosine-2'-O-)-methyltransferase [Salmonella enterica su... gi\|224586209, gi... - gi\|224586209\|ref\|YP_002640008.1\| putative tRNA/rRNA methyltransferase [Salmonella enterica subsp. en...	215.0	[0..42]	[291..2]

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Predicted Domain #1

Region A:
Residues: [1-294]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHRTARNFAE IKPNLLFRKA KMARKSAEKY VAKKIQVPEL QGEALFGLHS VLEAIRSGKR  60
   61 DFHSVFLKKA VENRADSDAR IKEILSRIDE LGIQKTLLTD DQLDRLTEFQ LHNGICMDAS 120
  121 ALQFSNFEPK TVSIFVDKVL DPGNLGAIGR SAWYFGADGL GLVKGRGPKS ITPAMIKSSC 180
  181 GALEHLPVQQ FLNFNEFRDK IKAAGGELVA TCDPGAAEKA GISAKSLDQW TPEKPVGIVL 240
  241 GDEGVGISRG ILNLCDTVIS ISPVRKDGSN VTSLNVSVVA GILLHHISLQ NRTN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	56.39794
Match:	1gz0A
Description:	RlmB, C-terminal domain; RlmB, N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
RNA methyltransferase activity	4.23455016472464	bayes_pls_golite062009
methyltransferase activity	3.59960278169345	bayes_pls_golite062009
transferase activity, transferring one-carbon groups	3.51722801996622	bayes_pls_golite062009
rRNA methyltransferase activity	3.14976989427746	bayes_pls_golite062009
RNA binding	2.61675538965988	bayes_pls_golite062009
tRNA methyltransferase activity	2.33123191403389	bayes_pls_golite062009
S-adenosylmethionine-dependent methyltransferase activity	2.23755555119187	bayes_pls_golite062009
tRNA (guanine) methyltransferase activity	2.14623472760939	bayes_pls_golite062009
nucleic acid binding	1.81000672982144	bayes_pls_golite062009
transferase activity	1.63934797352054	bayes_pls_golite062009
binding	1.31970199852267	bayes_pls_golite062009
structural constituent of ribosome	1.0137045454994	bayes_pls_golite062009
N-methyltransferase activity	0.736216022000293	bayes_pls_golite062009
structural molecule activity	0.694233763389628	bayes_pls_golite062009
rRNA (guanine) methyltransferase activity	0.319046095835882	bayes_pls_golite062009
catalytic activity	0.264002643439785	bayes_pls_golite062009
	0.16936231012632	bayes_pls_golite062009
snoRNA binding	0.155192244522672	bayes_pls_golite062009
protein binding	0.131685221037103	bayes_pls_golite062009
rRNA (guanine-N1-)-methyltransferase activity	6.26422903788337E-4	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: