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View Structure Prediction Details

Protein: CE18519
Organism: Caenorhabditis elegans
Length: 272 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE18519.

Description E-value Query
Range
Subject
Range
gi|109017861 - gi|109017861|ref|XP_001118147.1| PREDICTED: similar to dual specificity phosphatase 12 [Macaca mulat...
230.0 [0..1] [270..27]
DUSP12 - dual specificity phosphatase 12
gi|60656185, gi|... - gi|60656185|gb|AAX32656.1| dual specificity phosphatase 12 [synthetic construct], gi|123998709|gb|AB...
ENSPTRT00000002905 - null
230.0 [0..1] [270..27]
DUS12_RAT - Dual specificity protein phosphatase 12 OS=Rattus norvegicus GN=Dusp12 PE=2 SV=1
229.0 [0..3] [269..29]
DUS12_MOUSE - Dual specificity protein phosphatase 12 OS=Mus musculus GN=Dusp12 PE=2 SV=1
228.0 [0..3] [270..29]
gi|57111449 - gi|57111449|ref|XP_536142.1| PREDICTED: similar to dual specificity phosphatase 12 [Canis familiaris...
223.0 [0..1] [270..26]
gi|55593863 - gi|55593863|ref|XP_514446.1| PREDICTED: dual specificity phosphatase 12 [Pan troglodytes]
222.0 [0..1] [270..40]
gi|74268175 - gi|74268175|gb|AAI03263.1| DUSP12 protein [Bos taurus]
218.0 [0..1] [269..21]
gi|67677891, gi|... - gi|68448479|ref|NP_001020348.1| dual specificity phosphatase 12 [Danio rerio], gi|67677891|gb|AAH971...
210.0 [0..1] [269..1]
gi|83769229 - gi|83769229|dbj|BAE59366.1| unnamed protein product [Aspergillus oryzae]
gi|169773799 - gi|169773799|ref|XP_001821368.1| hypothetical protein [Aspergillus oryzae RIB40]
207.0 [0..1] [266..3]

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Predicted Domain #1
Region A:
Residues: [1-162]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MWKITENLYL AQLPMIVGPT SKQEFSKNDI KRVLTLTTEP ISEKQKIGGV DYKFLHLLDM  60
   61 PDEPILDNAI LETAVLYINE GVEKEENVGV HCLAAVSRSV SICAAYLMYK NQWPVEKALK 120
  121 MIESVRKTIG PNAGFLAQLK IWERSGMSFS ADQYKNLKID IP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 30.39794
Match: 1wrmA
Description: Crystal structure of JSP-1
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [163-272]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GITCVDSKTI WRQPVIDDQT KVRFKCRQCR KVIFNSDNIV HPLAEACQKY LIEPMAWLNV  60
   61 SGATCSVSHT CGAKLGTFIA SGSKCNGCNK FVRQWIFINR TKLDKVEIAT 

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 0.976
Match: 2cupA
Description: Solution structure of the Skeletal muscle LIM-protein 1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 3.05724284602407 bayes_pls_golite062009
binding 2.8684204787273 bayes_pls_golite062009
DNA binding 2.82694392055315 bayes_pls_golite062009
nucleic acid binding 2.67693765260774 bayes_pls_golite062009
transcription factor activity 2.19990269987205 bayes_pls_golite062009
protein binding 1.30321965120678 bayes_pls_golite062009
sequence-specific DNA binding 1.20569507423504 bayes_pls_golite062009
transcription activator activity 1.13340247022105 bayes_pls_golite062009
transcription factor binding 0.97712107394702 bayes_pls_golite062009
RNA polymerase II transcription factor activity 0.863365919140416 bayes_pls_golite062009
ligand-dependent nuclear receptor activity 0.799931773272387 bayes_pls_golite062009
transcription cofactor activity 0.161926196097185 bayes_pls_golite062009
catalytic activity 0.133319360419662 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 0.0993294811617091 bayes_pls_golite062009
structural constituent of ribosome 0.0849070471490733 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle