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View Structure Prediction Details

Protein: puf-3
Organism: Caenorhabditis elegans
Length: 502 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for puf-3.

Description E-value Query
Range
Subject
Range
gi|73979795 - gi|73979795|ref|XP_849088.1| PREDICTED: similar to pumilio homolog 2 isoform 1 [Canis familiaris]
429.0 [0..20] [501..597]

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Predicted Domain #1
Region A:
Residues: [1-132]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSQNTGSSNL GRYYESPPTA TEARGTFGGC FNANSSTNIW TPNRKVDSSM GFRSSSPTPQ  60
   61 SAWAPNRQGF GGQFSKWRTS TPMTTPARYP QQAVRLIDLE NNASFSKSLN STTRSHKCTL 120
  121 PIWAGDGEGN VS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [133-502]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DSVTLQDVLA NDALVEFATD KNGCRFLQEH YPTENDNDVH QKLFRKLVED RAIFLSLCSN  60
   61 MFGNFFVQRV LECSNTEEQE ILTEHLATDL YNLCLDKSAC RVIQLAIQKL DVHLATRLSL 120
  121 ELRDTHLVRL SIDQNGNHVI QKIVKTLPVS SWTFLVDFFA DDDNLIHVCQ DKYGCRVIQS 180
  181 TVETLSTDQY AQCYQHRVIL LRSLMAGVTR NCTQLASNEF ANYVVQHVIK CGDALAVYRD 240
  241 IIIEQCLLQN LLSMSQEKYA SHVVEVAFEC APYRLVAEMM NEIFEGYIPH PDTNRDALDI 300
  301 LLFHQYGNYV VQQMIQTCVL GQNARDQKQS EMYGMWLEKI HGRVMRNAHR LERFSSGKKI 360
  361 IEALQSMSLY 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 104.0
Match: 1ib2A
Description: Pumilio 1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.72717267135753 bayes_pls_golite062009
protein transporter activity 1.12211290620813 bayes_pls_golite062009
protein binding 1.01840651819417 bayes_pls_golite062009
transporter activity 0.89694340608107 bayes_pls_golite062009
substrate-specific transporter activity 0.40908371617242 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle