YRC Public Data Repository - Protein Structure Prediction

Protein:	CE18240
Organism:	Caenorhabditis elegans
Length:	178 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE18240.

Description	E-value	Query Range	Subject Range
pcbd-1 - status:Confirmed UniProt:Q9TZH6 protein_id:AAC67465.2	206.0	[0..37]	[178..1]
gi\|157745959 - gi\|157745959\|ref\|XP_001668076.1\| Hypothetical protein CBG03930 [Caenorhabditis briggsae AF16] gi\|39595301, gi\|... - gi\|39595301\|emb\|CAE60338.1\| Hypothetical protein CBG03930 [Caenorhabditis briggsae], gi\|187036132\|em...	184.0	[0..37]	[177..1]
gi\|157132864, gi... - gi\|157132864\|ref\|XP_001662676.1\| hypothetical protein AaeL_AAEL002898 [Aedes aegypti], gi\|108881639\|...	157.0	[0..64]	[178..106]
gi\|42794937, gi\|... - gi\|42794937\|gb\|AAS45834.1\| PCD/DCoH-like protein 2 [Arabidopsis thaliana], gi\|30690915\|ref\|NP_174274...	155.0	[0..2]	[175..12]
gi\|119113704, gi... - gi\|119113704\|ref\|XP_310658.3\| AGAP000439-PA [Anopheles gambiae str. PEST], gi\|116130486\|gb\|EAA06756....	155.0	[0..63]	[177..73]
gi\|73971304 - gi\|73971304\|ref\|XP_852425.1\| PREDICTED: similar to dimerization cofactor of hepatocyte nuclear facto...	151.0	[0..74]	[177..39]
gi\|46136631, gi\|... - gi\|46136631\|ref\|XP_390007.1\| hypothetical protein FG09831.1 [Gibberella zeae PH-1], gi\|42554850\|gb\|E...	149.0	[0..45]	[178..1]
gi\|94312465, gi\|... - gi\|94312465\|ref\|YP_585675.1\| pterin-4-alpha-carbinolamine dehydratase [Ralstonia metallidurans CH34]...	147.0	[0..64]	[177..10]

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Predicted Domain #1

Region A:
Residues: [1-178]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MINRYQLPLI CFLFTNTFYR LLPITVPFLL NASSHSMHSS YSHFLQRLRT SVSYLSVSHF  60
   61 PSTSSHRLFS TTIGVFARKK MPLLTESERT EQLSGLKTAG WKLVEGRDAI QKEFHFKDFN 120
  121 EAFGFMTRVG LKAEKMDHHP EWFNVYNKVD ITLSTHDCGG LSPNDVKLAT FIESIVKK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	35.522879
Match:	1ru0A
Description:	Crystal structure of DCoH2, a paralog of DCoH, the Dimerization Cofactor of HNF-1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
4-alpha-hydroxytetrahydrobiopterin dehydratase activity	6.27157822952381	bayes_pls_golite062009
transcription regulator activity	2.43253022834875	bayes_pls_golite062009
phenylalanine 4-monooxygenase activity	2.07153680701772	bayes_pls_golite062009
binding	1.91757396487631	bayes_pls_golite062009
transcription activator activity	1.76965686339133	bayes_pls_golite062009
protein binding	1.5922433129317	bayes_pls_golite062009
catalytic activity	1.39967796334655	bayes_pls_golite062009
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen	1.1107181321593	bayes_pls_golite062009
carbon-oxygen lyase activity	0.738746392707103	bayes_pls_golite062009
hydro-lyase activity	0.699903508958642	bayes_pls_golite062009
lyase activity	0.685050647082958	bayes_pls_golite062009
transcription factor binding	0.303837517417996	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: