YRC Public Data Repository - Protein Structure Prediction

Protein:	CE17610
Organism:	Caenorhabditis elegans
Length:	148 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE17610.

Description	E-value	Query Range	Subject Range
GCSH_ORYSI - Glycine cleavage system H protein, mitochondrial OS=Oryza sativa subsp. indica GN=GDCSH PE=2 SV=1 GCSH_ORYSA - Glycine cleavage system H protein, mitochondrial precursor - Oryza sativa (Rice) GCSH_ORYSJ - Glycine cleavage system H protein, mitochondrial OS=Oryza sativa subsp. japonica GN=GDCSH PE=1 SV=1	161.0	[0..2]	[146..19]
gi\|85719356 - gi\|85719356\|gb\|ABC75361.1\| 2-oxo acid dehydrogenase, lipoyl-binding site [Medicago truncatula]	158.0	[0..4]	[148..8]
GCSH_MESCR - Glycine cleavage system H protein, mitochondrial OS=Mesembryanthemum crystallinum GN=GDCSH PE=2 SV=1	158.0	[0..2]	[146..19]
GCSH_PEA - Glycine cleavage system H protein, mitochondrial OS=Pisum sativum GN=GDCSH PE=1 SV=1 gi\|68638223, gi\|... - gi\|68638228\|emb\|CAJ13838.1\| glycine decarboxylase multi-enzyme complex, H subunit [Pisum sativum sub... gi\|68638194 - gi\|68638194\|emb\|CAJ13833.1\| glycine decarboxylase multi-enzyme complex, H subunit [Pisum sativum sub... gi\|68609718, gi\|... - gi\|68609723\|emb\|CAJ13722.1\| H-protein of the glycine decarboxylase multi-enzyme complex [Pisum sativ... gi\|68638215 - gi\|68638215\|emb\|CAJ13836.1\| glycine decarboxylase multi-enzyme complex, H subunit [Pisum sativum var... gi\|68609771, gi\|... - gi\|68609771\|emb\|CAJ13732.1\| H-protein, glycine decarboxylase multi-enzyme complex [Pisum sativum sub... gi\|68609706, gi\|... - gi\|68609752\|emb\|CAJ13728.1\| H protein of the glycine decarboxylase multi-enzyme complex [Pisum fulvu... gi\|68609794, gi\|... - gi\|68609794\|emb\|CAJ13736.1\| H-protein from the glycine decarboxylase multi-enzyme complex [Pisum sat...	157.0	[0..9]	[148..26]
GCSH2_ARATH - Glycine cleavage system H protein 2, mitochondrial OS=Arabidopsis thaliana GN=GDH2 PE=2 SV=1	157.0	[0..4]	[148..12]
gi\|437993, gi\|21... - gi\|437993\|emb\|CAA81073.1\| H-protein [Flaveria cronquistii], pir\|\|S60195 glycine cleavage system prot... gi\|437999, gi\|36... - pir\|\|S60199 glycine cleavage system protein H precursor (clone HFP20) - Flaveria pringlei, gi\|43799...	157.0	[0..2]	[148..19]
gi\|2887286 - gi\|2887286\|emb\|CAB16710.1\| H protein [Flaveria anomala]	156.0	[0..2]	[148..19]
gi\|68609728 - gi\|68609728\|emb\|CAJ13723.1\| H-protein of the glycine decarboxylase multi-enzyme complex [Pisum sativ...	155.0	[0..9]	[148..26]

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Predicted Domain #1

Region A:
Residues: [1-148]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSFLSRFIPT VTARTAIRFA SNGRLYTKKH EWIVVNQSVG TVGITDFATE QLGDVVFIEL  60
   61 PEAGVEIEKG DSTGAVESVK AASDIYAPVS GKILEKNTKL EDEPGIINKS PLEKGWLYRL 120
  121 EITSNEQLNE LLTEEQYNKF KSEEEAEH

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	34.39794
Match:	1dxmA
Description:	Protein H of glycine cleavage system
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
aminomethyltransferase activity	7.15454688996532	bayes_pls_golite062009
glycine dehydrogenase (decarboxylating) activity	6.56199545993139	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor	6.56199545993139	bayes_pls_golite062009
acetyl-CoA carboxylase activity	2.30995434688093	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-NH2 group of donors	1.93346020821958	bayes_pls_golite062009
CoA carboxylase activity	1.92420834470262	bayes_pls_golite062009
ligase activity, forming carbon-carbon bonds	1.62422217856347	bayes_pls_golite062009
catalytic activity	1.39099902011318	bayes_pls_golite062009
ligase activity	0.56894584941056	bayes_pls_golite062009
binding	0.53993697366231	bayes_pls_golite062009
protein binding	0.396415237274882	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: