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View Structure Prediction Details

Protein: CE16735
Organism: Caenorhabditis elegans
Length: 433 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE16735.

Description E-value Query
Range
Subject
Range
GTF2E1 - general transcription factor IIE, polypeptide 1, alpha 56kDa
443.0 [0..16] [427..3]

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Predicted Domain #1
Region A:
Residues: [1-142]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSGPATSGS SSAHTETQVV DEIPEALNTI LLMVVKNFFS SEHFIIVYHI MRAQCIREEN  60
   61 LKARIQFDQK MLRQLLASLK AEKLVKERTI TQKNENNRTV SIIFYYINYR AVLNVVRYKI 120
  121 DHMRQKLESR EQMDTNRAHY RC

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 20.0
Match: 1q1hA
Description: An extended winged helix domain in general transcription factor E/IIE alpha
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 2.04426015975991 bayes_pls_golite062009
binding 1.99063774159045 bayes_pls_golite062009
DNA binding 1.63968725174405 bayes_pls_golite062009
nucleic acid binding 1.51035375793093 bayes_pls_golite062009
transcription factor activity 1.16072080355661 bayes_pls_golite062009
transcription activator activity 0.14130464856269 bayes_pls_golite062009
sequence-specific DNA binding 0.13573040816325 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [143-178]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GACQSSYDML EINRILDAES GRLICWRCHG DVLADE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 16.30103
Match: 1vd4A
Description: Solution structure of the zinc finger domain of TFIIE alpha
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.521842894436076 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [179-433]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TVVPSRTTRT AVARFNEQMT PLFSHICALN GIQLAPHLLE PDITKYLEDD KELQLQQQQM  60
   61 DFTSGGGGGG RIQLGGVAHS YQNIASINYQ NGDAVFVDLN ADINKGPVEE AKIMPEWLKD 120
  121 NAIGGGEASH NEHVLDQAKT EEEETSTKQR RYGPSLDYLK EIECSSEESA PNVKIEEPPA 180
  181 KQIKMEVDEE AIKMEVDNDE SEEEDLIHVA GRALPLSQIT PRMVENEMSE LEKESYCSVV 240
  241 QDLFAMFFSQ QIAIH

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle