YRC Public Data Repository - Protein Structure Prediction

Protein:	CE16643
Organism:	Caenorhabditis elegans
Length:	153 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE16643.

Description	E-value	Query Range	Subject Range
ISU3_ARATH - Iron-sulfur cluster assembly protein 3 OS=Arabidopsis thaliana GN=ISU3 PE=2 SV=1	212.0	[0..1]	[152..1]
CG9836-PA - This gene is referred to in FlyBase by the symbol Dmel\CG9836 (CG9836, FBgn0037637). It is a protein... gi\|195330562, gi... - gi\|195330562\|ref\|XP_002031972.1\| GM26300 [Drosophila sechellia], gi\|194120915\|gb\|EDW42958.1\| GM26300... gi\|220954788, gi... - gi\|220954788\|gb\|ACL89937.1\| CG9836-PA [synthetic construct], gi\|220944960\|gb\|ACL85023.1\| CG9836-PA [...	212.0	[0..2]	[152..1]
gi\|125777151, gi... - gi\|54639256\|gb\|EAL28658.1\| GA22065 [Drosophila pseudoobscura pseudoobscura], gi\|125777151\|ref\|XP_001... gi\|195152936, gi... - gi\|195152936\|ref\|XP_002017392.1\| GL22284 [Drosophila persimilis], gi\|194112449\|gb\|EDW34492.1\| GL2228... gi\|125777151\|ref... - GA22065-PA [Drosophila pseudoobscura], GA22065 [Drosophila pseudoobscura pseudoobscura]	211.0	[0..2]	[153..1]
gi\|47226486 - gi\|47226486\|emb\|CAG08502.1\| unnamed protein product [Tetraodon nigroviridis]	208.0	[0..3]	[151..6]
gi\|157104331, gi... - gi\|157104331\|ref\|XP_001648357.1\| nitrogen fixation protein nifu [Aedes aegypti], gi\|108880341\|gb\|EAT...	208.0	[0..2]	[151..4]
gi\|187021875, gi... - gi\|39584516\|emb\|CAE74594.1\| Hypothetical protein CBG22375 [Caenorhabditis briggsae], gi\|187021875\|em...	206.0	[0..1]	[153..1]
gi\|58387816, gi\|... - gi\|58387816\|ref\|XP_315834.2\| AGAP005813-PA [Anopheles gambiae str. PEST], gi\|55238630\|gb\|EAA10764.2\|... AGAP005813-PA - FeS cluster assembly scaffold IscU\|protein_coding\|2L:21632740:21633195:1\|gene:AGAP005813	206.0	[0..15]	[151..12]
gi\|20381021 - gi\|20381021\|gb\|AAH28800.1\| Iscu protein [Mus musculus]	206.0	[0..3]	[152..8]
gi\|76573610 - gi\|76573610\|dbj\|BAE44694.1\| hypothetical protein [Candida albicans] gi\|68469194, gi\|... - gi\|77022706\|ref\|XP_888797.1\| hypothetical protein CaO19_6548 [Candida albicans SC5314], gi\|68470219\|...	206.0	[0..5]	[149..14]
gi\|109497403, gi... - gi\|27666566\|ref\|XP_213811.1\| PREDICTED: similar to nitrogen fixation cluster-like [Rattus norvegicus...	205.0	[0..3]	[152..9]

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Predicted Domain #1

Region A:
Residues: [1-153]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLQISSAAK TLLHKFALPA ATSVAQYHEK VIDHYENPRN VGSLDKNDPS VGTGIVGAPA  60
   61 CGDVMKLQIR VDDNGKIIEA KFKTFGCGSA IASSSLATEW INGKTIDYAS KIKNDEIAKE 120
  121 LCLPPVKLHC SMLAQDAIQA ALKDYQKKQT KKA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	52.0
Match:	1q48A
Description:	Solution NMR Structure of The Haemophilus Influenzae Iron-Sulfur Cluster Assembly Protein U (IscU) with Zinc Bound at the Active Site. Northeast Structural Genomics Consortium Target IR24. This protein is not apo, it is a model without zinc binding constr
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	1.4500214796709	bayes_pls_golite062009
protein binding	0.380604392484225	bayes_pls_golite062009
catalytic activity	0.256292883613773	bayes_pls_golite062009
2 iron, 2 sulfur cluster binding	0.0439466134407704	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: