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View Structure Prediction Details

Protein: dnj-12
Organism: Caenorhabditis elegans
Length: 402 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for dnj-12.

Description E-value Query
Range
Subject
Range
gi|114624360 - gi|114624360|ref|XP_001154348.1| PREDICTED: similar to DnaJ-like protein [Pan troglodytes]
369.0 [0..1] [402..100]

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Predicted Domain #1
Region A:
Residues: [1-93]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVKETGYYDV LGVKPDASDN ELKKAYRKMA LKFHPDKNPD GAEQFKQISQ AYEVLSDEKK  60
   61 RQIYDQGGEE ALQGGGGGGE GFHNPFDVFD MFF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 21.0
Match: 2ochA
Description: No description for 2ochA was found.

Predicted Domain #2
Region A:
Residues: [94-402]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GGGGRGGRGE RRVKPTVHNL RVTLDTLYKG VTKKLKISRT ATCKGCKGLG GNEGSAKECS  60
   61 DCRGRGIKVR VIRMGPMVQQ MQSHCDSCNG EGSTFLEKDR CKKCNGKKQV KEDEIIEVGI 120
  121 TPGMKDGEKF VFEGKGDEVI GIEKPGDFVV VLDEVEHEKF VRKGDNLIIQ HNIDLSEALC 180
  181 GFVRTISTLD GRTIFYRVLP GEVIAHADVK VIHNEGMPMR RASSDKGDLL VQFDVKFPDK 240
  241 INPDAAKKLA DLLPGKREEI IDEDAEVVEL TELDPQASRR NFAERDDFEG HGGFGGHGHG 300
  301 PQGVQCQQS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 46.0
Match: 1nltA
Description: The crystal structure of Hsp40 Ydj1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.7298921704023 bayes_pls_golite062009
protein binding 2.6297172985864 bayes_pls_golite062009
protein disulfide isomerase activity 2.4409950647303 bayes_pls_golite062009
intramolecular oxidoreductase activity, transposing S-S bonds 2.4409950647303 bayes_pls_golite062009
intramolecular oxidoreductase activity, interconverting keto- and enol-groups 2.23398279564144 bayes_pls_golite062009
unfolded protein binding 2.04158808514315 bayes_pls_golite062009
receptor binding 1.01508461105961 bayes_pls_golite062009
catalytic activity 0.276917867171685 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle