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View Structure Prediction Details

Protein: lmn-1
Organism: Caenorhabditis elegans
Length: 566 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for lmn-1.

Description E-value Query
Range
Subject
Range
gi|114560153 - gi|114560153|ref|XP_513875.2| PREDICTED: lamin A/C [Pan troglodytes]
333.0 [0..19] [553..441]

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Predicted Domain #1
Region A:
Residues: [1-83]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSRKGTRSS RIVTLERSAN SSLSNNGGGD DSFGSTLLET SRLQEKDHLT SLNSRLATYI  60
   61 DKVRQLEQEN NRLQVQIRDI EVV

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [84-136]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EKKEKSNLAD RFEAEKARLR RALDSAQDEL AKYRIEYDAA KVEVKKLKPQ VEK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 9.09691
Match: 1c1gA
Description: Tropomyosin
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [137-480]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LERELAGAEE QALHAQSIAD QSQAKQKTLQ ARNDKLVVEN DDLKKQNITL RDTVEGLKKA  60
   61 VEDETLLRTA ANNKIKALEE DLAFALQQHK GELEEVRHKR QVDMTTYAKQ INDEYQSKLQ 120
  121 DQIEEMRAQF KNNLHQNKTA FEDAYKNKLN AARERQEEAV SEAIHLRARV RDLETSSSGN 180
  181 ASLIERLRSE LDTLKRSFQE KLDDKDARIA ELNQEIERMM SEFHDLLDVK IQLDAELKTY 240
  241 QALLEGEEER LNLTQEAPQN TSVHHVSFSS GGASAQRGVK RRRVVDVNGE DQDIDYLNRR 300
  301 SKLNKETVGP VGIDEVDEEG KWVRVANNSE EEQSIGGYKL VVKA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 16.39794
Match: 1i84S
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [481-566]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GNKEASFQFS SRMKLAPHAS ATVWSADAGA VHHPPEVYVM KKQQWPIGDN PSARLEDSEG  60
   61 DTVSSITVEF SESSDPSDPA DRCSIM

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 32.39794
Match: 1ivtA
Description: Lamin A/C globular tail domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
structural molecule activity 2.40638781086824 bayes_pls_golite062009
binding 2.29024114419453 bayes_pls_golite062009
protein binding 2.1850626714936 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle