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View Structure Prediction Details

Protein: cav-2
Organism: Caenorhabditis elegans
Length: 351 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for cav-2.

Description E-value Query
Range
Subject
Range
gi|1854942, gi|3... - ref|NP_506357.2| caveolin (40.8 kD) (cav-2) [Caenorhabditis elegans], gi|2493549|sp|Q18879.2|CAV2_C...
564.0 [0..1] [351..1]

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Predicted Domain #1
Region A:
Residues: [1-220]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTRQNTSESD NTQRPPIPQY DTVDDIDELT DAMDKEDHHH HHHHHEHHHQ HQGIAQYDTV  60
   61 EEVETLETVH HRTSLNQEVP TPQRRSHPQY DNLDDIDDQE YITEVEVKSN RGSTLTTRPH 120
  121 VTIKQDEIED IGERQVTVIE IASQKGSTKR VAPRKDYAPS IPLPEHPAQQ SAPPTQQSRP 180
  181 QTTSHKPPNP EMEFDIGVKN IAPVLIHKMN MDDRDPKDSA 

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 0.966
Match: 2apoA
Description: Crystal Structure of the Methanococcus jannaschii Cbf5 Nop10 Complex
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.752067860167757 bayes_pls_golite062009
pseudouridine synthase activity 0.238084857118933 bayes_pls_golite062009
catalytic activity 0.194390467213858 bayes_pls_golite062009
protein binding 0.0955723077565195 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [221-351]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QYLNTSFFEV FNEPSEQYHS IACVWTLSFK IFEIVRIYSY KILTLIFGLI IAFLGGILFA  60
   61 LFAFLNIWIF RPILILTRMA FAQIVLIWPM FLIYIVRPFF YSVGAIFSTA RLHTSRGEQV 120
  121 VEVWEKHIHH V

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 40.187087
Match: PF01146.8
Description: No description for PF01146.8 was found.

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle