YRC Public Data Repository - Protein Structure Prediction

Protein:	coq-3
Organism:	Caenorhabditis elegans
Length:	268 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for coq-3.

Description	E-value	Query Range	Subject Range
UBIG_PASMU - 3-demethylubiquinone-9 3-methyltransferase OS=Pasteurella multocida GN=ubiG PE=3 SV=1 UBIG_PASMU - Ubiquinone biosynthesis O-methyltransferase OS=Pasteurella multocida (strain Pm70) GN=ubiG PE=3 SV=1	183.0	[0..25]	[266..1]
gi\|90331742, gi\|... - gi\|90416543\|ref\|ZP_01224474.1\| 3-demethylubiquinone-9 3-methyltransferase [marine gamma proteobacter... gi\|90416543\|ref\|... - 3-demethylubiquinone-9 3-methyltransferase [marine gamma proteobacterium HTCC2207]	180.0	[0..18]	[267..4]
gi\|45520389, gi\|... - gi\|91775929\|ref\|YP_545685.1\| 3-demethylubiquinone-9 3-methyltransferase [Methylobacillus flagellatus...	179.0	[0..27]	[267..2]
UBIG_COXBN - Ubiquinone biosynthesis O-methyltransferase OS=Coxiella burnetii (strain Dugway 5J108-111) GN=ubiG P... gi\|94491372, gi\|... - gi\|94491372\|ref\|ZP_01298585.1\| hypothetical protein CburD_01001500 [Coxiella burnetii Dugway 7E9-12]...	179.0	[0..22]	[265..2]
UBIG_PSEAB - Ubiquinone biosynthesis O-methyltransferase OS=Pseudomonas aeruginosa (strain UCBPP-PA14) GN=ubiG PE... gi\|107102701 - gi\|107102701\|ref\|ZP_01366619.1\| hypothetical protein PaerPA_01003767 [Pseudomonas aeruginosa PACS2] gi\|126195237, gi... - gi\|84326079\|ref\|ZP_00974109.1\| COG2227: 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol met... gi\|84319998, gi\|... - gi\|84319998\|ref\|ZP_00968384.1\| COG2227: 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol met...	179.0	[0..25]	[267..1]
UBIG_PSEF5 - Ubiquinone biosynthesis O-methyltransferase OS=Pseudomonas fluorescens (strain Pf-5 / ATCC BAA-477) ...	178.0	[0..25]	[267..1]
UBIG_VIBPA - 3-demethylubiquinone-9 3-methyltransferase OS=Vibrio parahaemolyticus GN=ubiG PE=3 SV=1 UBIG_VIBPA - Ubiquinone biosynthesis O-methyltransferase OS=Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2...	178.0	[0..23]	[267..2]
gi\|89081582, gi\|... - gi\|89094107\|ref\|ZP_01167050.1\| 3-demethylubiquinone-9 3-methyltransferase [Oceanospirillum sp. MED92...	178.0	[0..17]	[267..1]
gi\|49082032 - gi\|49082032\|gb\|AAT50416.1\| PA3171 [synthetic construct]	178.0	[0..25]	[267..1]
UBIG_COXBU - Ubiquinone biosynthesis O-methyltransferase OS=Coxiella burnetii (strain RSA 493 / Nine Mile phase I... UBIG_COXB2 - Ubiquinone biosynthesis O-methyltransferase OS=Coxiella burnetii (strain CbuG_Q212) GN=ubiG PE=3 SV=... UBIG_COXBR - Ubiquinone biosynthesis O-methyltransferase OS=Coxiella burnetii (strain RSA 331 / Henzerling II) GN... UBIG_COXBU - 3-demethylubiquinone-9 3-methyltransferase OS=Coxiella burnetii GN=ubiG PE=3 SV=1	178.0	[0..22]	[265..2]

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Predicted Domain #1

Region A:
Residues: [1-268]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIPSRSARII AKLQRLHSTT SAASVSSIDV KEVEKFGDLS AEWADELGPF HALHSLNRIR  60
   61 VPWIVDNVRK SDQKAPPRLV DVGSGGGLLS IPLARSGFDV TGIDATKQAV EAANQSLTAK 120
  121 PLQIAGISKR LRFEHTSVED FCQKPHNKSA YDAVVASEIV EHVADLPGFI GCLAELARPG 180
  181 APLFITTINR TWLSKLAAIW LAENVLKIVP PGVHDWEKFI TPAELTSHLE KAGCRVTAVH 240
  241 GLMFHPVGNH WTWIESTQCN YGILAVKN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	24.221849
Match:	2fk7A
Description:	Crystal structure of Hma (MmaA4) from Mycobacterium tuberculosis, apo-form
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	1.25333584501255	bayes_pls_golite062009
transferase activity	1.07321114919891	bayes_pls_golite062009
transferase activity, transferring one-carbon groups	0.612108481676679	bayes_pls_golite062009
methyltransferase activity	0.606225212585352	bayes_pls_golite062009
S-adenosylmethionine-dependent methyltransferase activity	0.14147363365106	bayes_pls_golite062009
binding	0.109975487409217	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: