YRC Public Data Repository - Protein Structure Prediction

Protein:	nduf-7
Organism:	Caenorhabditis elegans
Length:	199 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for nduf-7.

Description	E-value	Query Range	Subject Range
gi\|157746691 - gi\|157746691\|ref\|XP_001668441.1\| Hypothetical protein CBG12445 [Caenorhabditis briggsae AF16] NDUS7_CAEBR - Probable NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial OS=Caenorhabditis brig...	264.0	[0..1]	[199..1]
gi\|39971881, gi\|... - gi\|39971881\|ref\|XP_367331.1\| hypothetical protein MG07256.4 [Magnaporthe grisea 70-15], gb\|EAA56901....	242.0	[0..1]	[199..863]
gi\|34189943 - gi\|34189943\|gb\|AAH01715.2\| NDUFS7 protein [Homo sapiens]	242.0	[0..6]	[199..18]
gi\|58381050, gi\|... - gi\|58381050\|ref\|XP_310968.2\| AGAP000170-PA [Anopheles gambiae str. PEST], gi\|55243649\|gb\|EAA06474.3\|... AGAP000170-PA - NADH dehydrogenase (ubiquinone) Fe-S protein 7\|protein_coding\|X:2905106:2905729:-1\|gene:AGAP000170	241.0	[0..2]	[199..12]
gi\|113197754, gi... - gi\|118404166\|ref\|NP_001072396.1\| hypothetical protein LOC779850 [Xenopus (Silurana) tropicalis], gi\|...	241.0	[0..6]	[199..18]
NDUS7_PANTR - NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial OS=Pan troglodytes GN=NDUFS7 PE...	241.0	[0..6]	[199..23]
NDUS7_PONAB - NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial OS=Pongo abelii GN=NDUFS7 PE=2 ... NDUS7_PONPY - NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial precursor - Pongo pygmaeus (Ora...	241.0	[0..7]	[199..24]

Back

Predicted Domain #1

Region A:
Residues: [1-199]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLSALRTAGA VGTRRLASTQ AIASNSEAPK GIATTGTPFL NPSSKAEYAL ARLDDVLNLA  60
   61 QRGSIWPLTF GLACCAVEMM HFAAPRYDMD RYGVVFRASP RQADLIFVAG TVTNKMAPAL 120
  121 RRIYDQMPEA KWVISMGSCA NGGGYYHYAY SVLRGCDRVI PVDIYVPGCP PTAEALLYGV 180
  181 LQLQKKIKRK REAQLWYRR

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	49.69897
Match:	2fug6
Description:	Crystal structure of the hydrophilic domain of respiratory complex I from Thermus thermophilus
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
NADH dehydrogenase activity	13.9361001493201	bayes_pls_golite062009
NADH dehydrogenase (quinone) activity	12.823760326196	bayes_pls_golite062009
NADH dehydrogenase (ubiquinone) activity	12.8237449606378	bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor	12.2946357205778	bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH	11.5463682902166	bayes_pls_golite062009
oxidoreductase activity	6.65509281399906	bayes_pls_golite062009
oxidoreduction-driven active transmembrane transporter activity	3.12366321374445	bayes_pls_golite062009
4 iron, 4 sulfur cluster binding	2.30490418238429	bayes_pls_golite062009
catalytic activity	1.41356903593784	bayes_pls_golite062009
iron-sulfur cluster binding	1.3943220140881	bayes_pls_golite062009
metal cluster binding	1.3943220140881	bayes_pls_golite062009
binding	1.12857450780286	bayes_pls_golite062009
protein binding	0.241603585422086	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: