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View Structure Prediction Details

Protein: cdc-37
Organism: Caenorhabditis elegans
Length: 370 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for cdc-37.

Description E-value Query
Range
Subject
Range
gi|50748728 - gi|50748728|ref|XP_421380.1| PREDICTED: similar to KIAA1124 protein [Gallus gallus]
183.0 [0..40] [370..747]

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Predicted Domain #1
Region A:
Residues: [1-139]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPIDYSKWKD IEVSDDEDDT HPNIDTPSLF RWRHQARLER MAEKKMEQEK IDKEKGTTSK  60
   61 KMEELEKKLA AADVTDKSDI QKQIDEVKAQ EEAWRKKEAE LEEKERLEPW NVDTIGHEAF 120
  121 STSRINKITE KKPQAPKTD

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 56.040959
Match: PF03234.5
Description: No description for PF03234.5 was found.

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [140-370]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EEDTHAMSTF FETHESLLEK MAVLKNGAKS TELFLAEHPH MASEYTANWL TIEALNAAID  60
   61 FNEEKMKTMA EQCIIIQYLL ELSKSLNAVA TNTTVQKQFF KKFEAAEPVY MKHYQDEVKA 120
  121 FEDRLRTRAQ TKRDAAMEEA EAEEKAERMK SAPGGIDPQE VFEQLPEEMR KCFEAHDIEA 180
  181 LKGVAQKMDE EVFKYHFDRC IASGLWVPGK ADDDDDDEEA APAEEEPTTS S

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 25.154902
Match: 1us7B
Description: Complex of Hsp90 and P50
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.63059449218992 bayes_pls_golite062009
protein binding 0.967371813449539 bayes_pls_golite062009
unfolded protein binding 0.68193901105298 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle