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View Structure Prediction Details

Protein: CE14458
Organism: Caenorhabditis elegans
Length: 386 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE14458.

Description E-value Query
Range
Subject
Range
gi|74000787 - gi|74000787|ref|XP_867217.1| PREDICTED: similar to high-mobility group 20A isoform 3 [Canis familiar...
212.0 [0..14] [379..7]

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Predicted Domain #1
Region A:
Residues: [1-105]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRPRRSDSTT GPAAKSLPTS DVEEDEAAPD LKAESEDVTS SEEMQNKNPV SAPEKRAKTA  60
   61 SFSPPPALSP AHSIQMENEE IEVKMEVDSD EEEKKLPKIT EKRAK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 7.0
Match: 1aabA
Description: NMR STRUCTURE OF RAT HMG1 HMGA FRAGMENT
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.26567769591593 bayes_pls_golite062009
nucleic acid binding 0.818311652354687 bayes_pls_golite062009
DNA binding 0.811818342611352 bayes_pls_golite062009
protein binding 0.751190715138185 bayes_pls_golite062009
transcription regulator activity 0.381276648599631 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [106-221]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVYKKKPEKE KEAVPFIDPN APKRNRSGYV HFIIHRRASY SKAVMSQREI NISLAADWQK  60
   61 LTAEERIPFQ QRADEEKVKY LELMEEYKKT DSHKEFQKKR AKFLSSQSNG SKNAKK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 17.221849
Match: 2gzkA
Description: No description for 2gzkA was found.

Predicted functions:

Term Confidence Notes
binding 2.26567769591593 bayes_pls_golite062009
nucleic acid binding 0.818311652354687 bayes_pls_golite062009
DNA binding 0.811818342611352 bayes_pls_golite062009
protein binding 0.751190715138185 bayes_pls_golite062009
transcription regulator activity 0.381276648599631 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [222-386]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RRQADSDDDT PNVQIPFPKP SVFCPLLSPE PATSSSTSGL QYSGPIFTPE FMTYNKTRDT  60
   61 YRRQLAIERS HVEHELEALH QHDMDVRIEQ QETRIREADE KIEETMAKMR TVLAAVPGAK 120
  121 DHLTSIDALA TWLESLTHLG AQNSTKKSVK EAVNKNAKSI VQMKK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 6.221849
Match: 1v63A
Description: Solution structure of the 6th HMG box of mouse UBF1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.26567769591593 bayes_pls_golite062009
nucleic acid binding 0.818311652354687 bayes_pls_golite062009
DNA binding 0.811818342611352 bayes_pls_golite062009
protein binding 0.751190715138185 bayes_pls_golite062009
transcription regulator activity 0.381276648599631 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle