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View Structure Prediction Details

Protein: sup-12
Organism: Caenorhabditis elegans
Length: 248 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for sup-12.

Description E-value Query
Range
Subject
Range
gi|73976797 - gi|73976797|ref|XP_857696.1| PREDICTED: similar to poly(A) binding protein, cytoplasmic 4 isoform 1 ...
151.0 [0..2] [228..233]
gi|76689263 - gi|76689263|ref|XP_880772.1| PREDICTED: similar to poly(A) binding protein, cytoplasmic 4 isoform 1 ...
151.0 [0..2] [224..233]
gi|94732878 - gi|94732878|emb|CAK04913.1| novel protein containing RNA recognition motifs (a.k.a. RRM, RBD, or RNP...
148.0 [0..9] [248..42]
gi|55957843 - gi|55957843|emb|CAI13378.1| ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen ...
ENSMMUT000000140... - null, null
ENSPTRT00000038537 - null
ENSCJAT00000015741 - null
148.0 [0..22] [248..54]
gi|74189486 - gi|74189486|dbj|BAE22747.1| unnamed protein product [Mus musculus]
147.0 [0..2] [227..162]

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Predicted Domain #1
Region A:
Residues: [1-132]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MYGQVQDPLV HAAAAALAQS TNAEPVVGSR DTMFTKIFVG GLPYHTSDKT LHEYFEQFGD  60
   61 IEEAVVITDR NTQKSRGYGF VTMKDRASAE RACKDPNPII DGRKANVNLA YLGAKPRTNV 120
  121 QLAALAAGQV QL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 24.39794
Match: 2cqdA
Description: Solution Structure of the RNA recognition motif in RNA-binding region containing protein 1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA binding 3.75748736237159 bayes_pls_golite062009
nucleic acid binding 3.30499161454806 bayes_pls_golite062009
mRNA binding 2.67679675039933 bayes_pls_golite062009
binding 2.30438455421982 bayes_pls_golite062009
0.61507045441317 bayes_pls_golite062009
single-stranded RNA binding 0.61170301639809 bayes_pls_golite062009
protein binding 0.403675976995418 bayes_pls_golite062009
transcription regulator activity 0.361110886317161 bayes_pls_golite062009
DNA binding 0.139895000724487 bayes_pls_golite062009
poly-pyrimidine tract binding 0.0800614106161897 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [133-248]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PLTTQLQALF QPRMGLPQMY YPTVTGLVNP LMAQQGAAAQ QQLFDYNALA AVMNPQAAAA  60
   61 YGIQSQGKFA AAPTTIEQYA AYPAGYGLVP QSAYNIGNPQ LQQLAAAQQQ LEHQRV

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle