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View Structure Prediction Details

Protein: htp-3
Organism: Caenorhabditis elegans
Length: 739 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for htp-3.

Description E-value Query
Range
Subject
Range
gi|109016438 - gi|109016438|ref|XP_001106338.1| PREDICTED: similar to HORMA domain containing 1 [Macaca mulatta]
276.0 [0..26] [393..21]

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Predicted Domain #1
Region A:
Residues: [1-283]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDESFDSSVV PGSLTSDDRA IFNEQTLKNG DENSKSSLEV MANCVYLANS TILRERKVIP  60
   61 AEYFQDFQVY GDVSGYTLRQ DIPEGRSVSS KLLASHDAIR QKLLQKLAIV VEESLNTNPV 120
  121 ETFVWTFVYD STTSASAEIG YGGRKSKFVV NYLNMDDTAQ QFCKMFSELR NVLSLLRPLP 180
  181 RGLIPSMKVA YRGEPEFVPG FQQVDDFVNP EQINLGAVSF PHGNGFQFAY ASKFMVEQPS 240
  241 AIRPPVEVSH FEDDLLNSTI TPIEVVRDNT MNCAENPELD EIY

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 3.75
Match: 1s2hA
Description: The Mad2 spindle checkpoint protein possesses two distinct natively folded states
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.643047718552136 bayes_pls_golite062009
protein binding 0.123037566638484 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [284-393]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FSPGRQEVRM DEDVANESIR CNPSMASEMM VLQSEYNVLI ADNDEVPMVV ERERSPIVKA  60
   61 AKKRSTRAPA VPITPTEPAS PVESPVKEQP QKAPKAQMRR SSKRTTKNNE 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [394-569]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RCEQKEEEPI VNPKRRSARR LVPPVEVDEQ PEEQNDDDAQ NSLQIDSDAQ NSLQIDSDAI  60
   61 ITSPEKRNES KSAIPEEAAD LDNTTSEKQE SSTARYGVSN TSINRKKPDP VANPVSEEAQ 120
  121 VDLANGSIPD KRPRKRKYGR VSSILDVADL PTDDTVEEDV RESPIYGRVP SILDVA

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [570-739]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RAEENDAQND AQDAQNEIAV EGLADLSIDT EQHEEAAPIN VTGHQSESVP IIVTEHQSEE  60
   61 AQTVVTEQPA GAASVIAAER HYGRVSSILD VAGSFADVDP SGAAPAIATE RHYGRVSSIL 120
  121 DVAGSLSDVD PQEDTESSTQ NQSTSKKFKP NPPKAMRYGQ SPNMPSRRGN 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


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