YRC Public Data Repository - Protein Structure Prediction

Protein:	his-8
Organism:	Caenorhabditis elegans
Length:	123 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for his-8.

Description	E-value	Query Range	Subject Range
gi\|187036007, gi... - gi\|39595176\|emb\|CAE60213.1\| Hypothetical protein CBG03777 [Caenorhabditis briggsae], gi\|187036007\|em... gi\|157745709 - gi\|157745709\|ref\|XP_001667951.1\| Hypothetical protein CBG03777 [Caenorhabditis briggsae AF16]	213.0	[0..1]	[123..1]
gi\|76656039 - gi\|76656039\|ref\|XP_593475.2\| PREDICTED: similar to rCG23123 [Bos taurus]	200.0	[0..6]	[123..225]
gi\|50728600 - gi\|50728600\|ref\|XP_416197.1\| PREDICTED: similar to H2B histone family, member F [Gallus gallus]	199.0	[0..2]	[123..74]
gi\|109016350 - gi\|109016350\|ref\|XP_001104697.1\| PREDICTED: similar to Histone H2B 291B [Macaca mulatta]	195.0	[0..2]	[123..70]
gi\|74012717 - gi\|74012717\|ref\|XP_545431.2\| PREDICTED: similar to Histone H2B 291B, partial [Canis familiaris]	195.0	[0..2]	[118..5]
gi\|149029297, gi... - gi\|62663602\|ref\|XP_214483.3\| PREDICTED: similar to Histone H2B 291B [Rattus norvegicus], gi\|14902929...	193.0	[0..2]	[123..5]

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Predicted Domain #1

Region A:
Residues: [1-123]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAPPKPSAKG AKKAAKTVTK PKDGKKRRHA RKESYSVYIY RVLKQVHPDT GVSSKAMSIM  60
   61 NSFVNDVFER IAAEASRLAH YNKRSTISSR EIQTAVRLIL PGELAKHAVS EGTKAVTKYT 120
  121 SSK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	44.522879
Match:	2cv5D
Description:	Crystal structure of human nucleosome core particle
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	1.73700145395396	bayes_pls_golite062009
DNA binding	1.04127970884713	bayes_pls_golite062009
nucleic acid binding	0.86554830065808	bayes_pls_golite062009
transcription regulator activity	0.57702121108343	bayes_pls_golite062009
protein binding	0.260428734715028	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: