YRC Public Data Repository - Protein Structure Prediction

Protein:	CE09504
Organism:	Caenorhabditis elegans
Length:	249 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE09504.

Description	E-value	Query Range	Subject Range
gi\|255313843 - gi\|255313843\|ref\|ZP_05355426.1\| 3-oxoacyl-[acyl-carrier protein] reductase [Clostridium difficile QC... gi\|255516524 - gi\|255516524\|ref\|ZP_05384200.1\| 3-oxoacyl-[acyl-carrier protein] reductase [Clostridium difficile QC... gi\|255649624 - gi\|255649624\|ref\|ZP_05396526.1\| 3-oxoacyl-[acyl-carrier protein] reductase [Clostridium difficile QC... gi\|254974717 - gi\|254974717\|ref\|ZP_05271189.1\| 3-oxoacyl-[acyl-carrier protein] reductase [Clostridium difficile QC... gi\|255092105 - gi\|255092105\|ref\|ZP_05321583.1\| 3-oxoacyl-[acyl-carrier protein] reductase [Clostridium difficile CI... gi\|90575404, gi\|... - gi\|90575404\|ref\|ZP_01231888.1\| hypothetical protein CdifQ_02001165 [Clostridium difficile QCD-32g58]...	267.0	[0..1]	[248..4]
gi\|115250215, gi... - gi\|126698778\|ref\|YP_001087675.1\| 3-oxoacyl-[acyl-carrier protein] reductase [Clostridium difficile 6... gi\|255306086 - gi\|255306086\|ref\|ZP_05350258.1\| 3-oxoacyl-[acyl-carrier protein] reductase [Clostridium difficile AT... gi\|255100197 - gi\|255100197\|ref\|ZP_05329174.1\| 3-oxoacyl-[acyl-carrier protein] reductase [Clostridium difficile QC...	267.0	[0..1]	[248..4]
FABG_THEMA - 3-oxoacyl-[acyl-carrier-protein] reductase FabG OS=Thermotoga maritima GN=fabG PE=3 SV=1 FABG_THEMA - 3-oxoacyl-[acyl-carrier-protein] reductase FabG OS=Thermotoga maritima (strain ATCC 43589 / MSB8 / D...	265.0	[0..1]	[248..3]
gi\|53688164 - gi\|53688164\|ref\|ZP_00110036.2\| COG1028: Dehydrogenases with different specificities (related to shor...	263.0	[0..1]	[249..109]
gi\|18310052, gi\|... - gi\|18310052\|ref\|NP_561986.1\| 3-ketoacyl-(acyl-carrier-protein) reductase [Clostridium perfringens st...	261.0	[0..1]	[248..2]
gi\|146296617, gi... - gi\|82501013\|ref\|ZP_00886394.1\| 3-oxoacyl-(acyl-carrier-protein) reductase [Caldicellulosiruptor sacc...	261.0	[0..1]	[248..4]
gi\|53610584 - ref\|ZP_00342080.1\| COG1028: Dehydrogenases with different specificities (related to short-chain alco... gi\|67085961, gi\|... - gi\|67156772\|ref\|ZP_00418269.1\| Short-chain dehydrogenase/reductase SDR [Azotobacter vinelandii AvOP]...	260.0	[0..1]	[249..40]
gi\|219540094, gi... - gi\|68206640\|ref\|ZP_00558823.1\| Glucose/ribitol dehydrogenase [Desulfitobacterium hafniense DCB-2], g...	260.0	[0..1]	[246..3]
gi\|89098688, gi\|... - gi\|89098688\|ref\|ZP_01171570.1\| beta-ketoacyl-acyl carrier protein reductase [Bacillus sp. NRRL B-149...	259.0	[0..1]	[248..3]
YHDF_BACSU - Uncharacterized oxidoreductase yhdF OS=Bacillus subtilis GN=yhdF PE=3 SV=1 YHDF_BACSU - Uncharacterized oxidoreductase YhdF OS=Bacillus subtilis (strain 168) GN=yhdF PE=3 SV=1	259.0	[0..1]	[248..43]

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Predicted Domain #1

Region A:
Residues: [1-249]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAPKSILITG ANRGIGLGLL KQFIKNKDVQ IIIGTCRDPS NATELNSIKD TRVHILQLDI  60
   61 DCDDSIRKLG AEVEKLVGED GLTVLINNAG IFVPYDIDGE KSRSTLIRQL ETNTISTVLI 120
  121 TQELLPLLKR AAAKNRGEGY SINRSAIINI SSTAGSITKI DASYNIPLVA YRMSKSALNS 180
  181 FGKSCSVDLA KYHILVTTFC PGWVKTDMGG ANGKLEIDDA TKTLSDNILI LGDAHHGAYL 240
  241 NADLTVIPN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	28.69897
Match:	1yo6A
Description:	Crystal Structure of the putative Carbonyl Reductase Sniffer of Caenorhabditis elegans
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	1.79741889688267	bayes_pls_golite062009
structural molecule activity	1.60272619511594	bayes_pls_golite062009
binding	0.982999356179965	bayes_pls_golite062009
DNA binding	0.302492036575815	bayes_pls_golite062009
transcription regulator activity	0.177044638410302	bayes_pls_golite062009
nucleic acid binding	0.150346154405223	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: