| Protein: | hda-1 |
| Organism: | Caenorhabditis elegans |
| Length: | 461 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for hda-1.
| Description | E-value | Query Range |
Subject Range |
|
|
524.0 | [0..7] | [451..3] |
|
Region A: Residues: [1-388] |
1 11 21 31 41 51
| | | | | |
1 MNSNGPLMEH GKRRVAYYYD SNIGNYYYGQ GHVMKPHRIR MTHHLVLNYG LYRNLEIFRP 60
61 FPASFEDMTR FHSDEYMTFL KSANPDNLKS FNKQMLKFNV GEDCPLFDGL YEFCQLSSGG 120
121 SLAAATKLNK QKVDIAINWM GGLHHAKKSE ASGFCYTNDI VLGILELLKY HKRVLYVDID 180
181 VHHGDGVEEA FYTTDRVMTV SFHKYGDFFP GTGDLKDIGA GKGKLYSVNV PLRDGITDVS 240
241 YQSIFKPIMT KVMERFDPCA VVLQCGADSL NGDRLGPFNL TLKGHGECAR FFRSYNVPLM 300
301 MVGGGGYTPR NVARCWTYET SIAVDKEVPN ELPYNDYFEY FGPNYRLHIE SSNAANENSS 360
361 DMLAKLQTDV IANLEQLTFV PSVQMRPI
|
| Detection Method: |  |
| Confidence: | 94.0 |
| Match: | 1t64A |
| Description: | Crystal Structure of human HDAC8 complexed with Trichostatin A |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| protein deacetylase activity | 12.8220438463909 | bayes_pls_golite062009 |
| histone deacetylase activity | 12.6231784270509 | bayes_pls_golite062009 |
| deacetylase activity | 11.5037545953213 | bayes_pls_golite062009 |
| hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides | 9.39837596691907 | bayes_pls_golite062009 |
| hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds | 9.35288901670927 | bayes_pls_golite062009 |
| histone deacetylase activity (H3-K16 specific) | 6.99181745976945 | bayes_pls_golite062009 |
| histone deacetylase activity (H3-K14 specific) | 4.16874113003585 | bayes_pls_golite062009 |
| histone methyltransferase activity (H3-K27 specific) | 3.8227021325477 | bayes_pls_golite062009 |
| histone deacetylase activity (H3-K9 specific) | 3.65015413158247 | bayes_pls_golite062009 |
| transcription repressor activity | 3.49362347258099 | bayes_pls_golite062009 |
| NAD-dependent protein deacetylase activity | 3.35999169984456 | bayes_pls_golite062009 |
| NAD-dependent histone deacetylase activity | 3.35999169984456 | bayes_pls_golite062009 |
| transcription regulator activity | 3.05701986980927 | bayes_pls_golite062009 |
| transcription factor binding | 2.19991964087943 | bayes_pls_golite062009 |
| hydrolase activity | 2.17916401684365 | bayes_pls_golite062009 |
| NAD-independent histone deacetylase activity | 2.1026758793482 | bayes_pls_golite062009 |
| nucleic acid binding | 2.09632179671955 | bayes_pls_golite062009 |
| transcription corepressor activity | 1.98907367314887 | bayes_pls_golite062009 |
| DNA binding | 1.982290944939 | bayes_pls_golite062009 |
| binding | 1.948738669065 | bayes_pls_golite062009 |
| protein binding | 1.77599011146146 | bayes_pls_golite062009 |
| catalytic activity | 1.68836803454021 | bayes_pls_golite062009 |
| histone methyltransferase activity (H3-K9 specific) | 1.48241147541212 | bayes_pls_golite062009 |
| specific transcriptional repressor activity | 1.37118634909958 | bayes_pls_golite062009 |
| transcription activator activity | 1.31578100431097 | bayes_pls_golite062009 |
| transcription factor activity | 1.24596588472933 | bayes_pls_golite062009 |
| transcription cofactor activity | 0.84972377395539 | bayes_pls_golite062009 |
| histone methyltransferase activity | 0.396822865624511 | bayes_pls_golite062009 |
| transferase activity | 0.323230424038105 | bayes_pls_golite062009 |
| chromatin binding | 0.104097933861351 | bayes_pls_golite062009 |
|
Region A: Residues: [389-461] |
1 11 21 31 41 51
| | | | | |
1 PEDALSALND DSLIADQANP DKRLPPQITD GMIQDDGDFY DGEREGDDRR NESDAKRAAQ 60
61 FESEGGEKRQ KTE
|
| Detection Method: | |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
