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View Structure Prediction Details

Protein: bir-2
Organism: Caenorhabditis elegans
Length: 308 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for bir-2.

Description E-value Query
Range
Subject
Range
gi|112983200, gi... - gi|14248546|gb|AAK57560.1|AF281073_1 inhibitor of apoptosis protein [Bombyx mori], gi|112983200|ref|...
245.0 [0..10] [308..60]

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Predicted Domain #1
Region A:
Residues: [1-131]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPYTFENSEA LLKNLKDAAP YISAAERFAS FKGFVYDKRI NIACTSEKLA RAGFYSTASP  60
   61 EFPASAKCPF CMLEINFEQC DDPWEKHKSG SPHCEFVMIG EIEESELSFR IISNLAIRHA 120
  121 TVRLYEELLG I

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 27.154902
Match: 1m4mA
Description: Anti-apoptotic protein survivin
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
protein binding 1.08201190414623 bayes_pls_golite062009
binding 1.04832973985677 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [132-308]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VATLENGDIA NENPITRADA TRKLISFRSS SKLLTFDHRL ATFQNFIFDK KRNVKCTSKK  60
   61 LAKAGWFSIA NKKDKTSAKC PFCLVELDFD ESDDPWEEHQ KFSASCDFIK LGKLDEKKWT 120
  121 ENEALMLGAR ITIMQKYEKG SWLIDELEKE NRIDEIIKIR KIMIKPNHVL KRRRCSI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 27.221849
Match: 1jd4A
Description: BIR2 domain of DIAP1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
protein binding 1.08201190414623 bayes_pls_golite062009
binding 1.04832973985677 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle