YRC Public Data Repository - Protein Structure Prediction

Protein:	djr-1.2
Organism:	Caenorhabditis elegans
Length:	186 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for djr-1.2.

Description	E-value	Query Range	Subject Range
gi\|87286567, gi\|... - gi\|87310810\|ref\|ZP_01092937.1\| proteinase I [Blastopirellula marina DSM 3645], gi\|87286567\|gb\|EAQ784...	157.0	[0..2]	[171..4]
gi\|24981661, gi\|... - gi\|26987040\|ref\|NP_742465.1\| AraC family transcriptional regulator [Pseudomonas putida KT2440], gi\|2...	155.0	[0..4]	[186..15]
gi\|148545573, gi... - gi\|82739945\|ref\|ZP_00902721.1\| Helix-turn-helix, AraC type [Pseudomonas putida F1], gi\|82712969\|gb\|E...	155.0	[0..4]	[186..15]
gi\|76796858, gi\|... - gi\|76796858\|ref\|ZP_00779208.1\| Peptidase C56, PfpI [Thermoanaerobacter ethanolicus ATCC 33223], gi\|7... gi\|241904491, gi... - gi\|241904491\|ref\|ZP_04789183.1\| intracellular protease, PfpI family [Thermoanaerobacter brockii subs...	153.0	[0..6]	[168..2]
gi\|32397757, gi\|... - gi\|32473078\|ref\|NP_866072.1\| proteinase I [Rhodopirellula baltica SH 1], gi\|32397757\|emb\|CAD73758.1\|...	153.0	[0..2]	[178..5]
gi\|113941739, gi... - gi\|159897361\|ref\|YP_001543608.1\| PfpI family intracellular peptidase [Herpetosiphon aurantiacus ATCC...	153.0	[0..1]	[170..1]
gi\|255114788, gi... - gi\|255253661\|ref\|ZP_05333232.1\| intracellular protease, PfpI family [Thermoanaerobacter italicus Ab9... gi\|166854258, gi... - gi\|167040018\|ref\|YP_001663003.1\| PfpI family intracellular peptidase [Thermoanaerobacter sp. X514], ... gi\|242257006, gi... - gi\|242257006\|ref\|ZP_04801884.1\| intracellular protease, PfpI family [Thermoanaerobacter sp. X513], g...	153.0	[0..6]	[167..2]
gi\|19916492, gi\|... - gi\|20091359\|ref\|NP_617434.1\| intracellular protease I [Methanosarcina acetivorans C2A], gi\|19916492\|...	152.0	[0..7]	[170..2]
gi\|71739721, gi\|... - gi\|71839798\|ref\|ZP_00679539.1\| DJ-1 protein [Pelobacter propionicus DSM 2379], gi\|71739721\|gb\|EAO348...	152.0	[0..7]	[184..3]
PFPI_PYRFU - Intracellular protease 1 OS=Pyrococcus furiosus GN=pfpI PE=1 SV=1 PFPI_PYRFU - Intracellular protease 1 OS=Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1) GN=p...	151.0	[0..7]	[170..2]

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Predicted Domain #1

Region A:
Residues: [1-186]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAAQKSALIL LPPEDAEEIE VIVTGDVLVR GGLQVLYAGS STEPVKCAKG ARIVPDVALK  60
   61 DVKNKTFDII IIPGGPGCSK LAECPVIGEL LKTQVKSGGL IGAICAGPTV LLAHGIVAER 120
  121 VTCHYTVKDK MTEGGYKYLD DNVVISDRVI TSKGPGTAFE FALKIVETLE GPEKTNSLLK 180
  181 PLCLAK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	33.69897
Match:	1j42A
Description:	Crystal Structure of Human DJ-1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	1.30391542469987	bayes_pls_golite062009
binding	1.22860407524238	bayes_pls_golite062009
ligase activity	1.03859358394018	bayes_pls_golite062009
peptidase activity	0.819143099666235	bayes_pls_golite062009
nucleic acid binding	0.3972868364469	bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides	0.217251599372912	bayes_pls_golite062009
hydrolase activity	0.121916378202276	bayes_pls_golite062009
protein binding	0.0152024556625711	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: