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View Structure Prediction Details

Protein: CE06744
Organism: Caenorhabditis elegans
Length: 631 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE06744.

Description E-value Query
Range
Subject
Range
RHM1_ARATH - Trifunctional UDP-glucose 4,6-dehydratase/UDP-4-keto-6-deoxy-D-glucose 3,5-epimerase/UDP-4-keto-L-rh...
408.0 [0..2] [622..3]

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Predicted Domain #1
Region A:
Residues: [1-339]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVYTPKNVVI TGGCGFIGSN FVNYIHDAWP TCNFVNIDKL ILNSDTQNVA ESVRNSPRYK  60
   61 LVLTDIKNEA AILNVFEQNE IDTVIHFAAD CTSTRCYNET AEAVQNNVLS FIQFLETVRT 120
  121 YGKIKRFVHI STDEVYGDSD LSENEQGKVE FSRLVPGNPY AATKIAGEAY VRAYQTQYNL 180
  181 PIVTARMNNI YGPNQWDVKV VPRFIEIAKV RGEYTIQGSG KQLRSWLFVD DASAGLKAVC 240
  241 EKGELHEIYN LGTYYEKNVA DLAKTIQEEV DLQLGRAHEP PKYKSIPDRP YNDLRYLISI 300
  301 EKAKNDLGWE PTTSFDDGMR HTVASALKEH KHVKMHVAI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 92.09691
Match: 1g1aA
Description: dTDP-glucose 4,6-dehydratase (RmlB)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
UDP-glucose 4-epimerase activity 2.13934644118967 bayes_pls_golite062009
catalytic activity 1.79741889688267 bayes_pls_golite062009
oxidoreductase activity, acting on CH-OH group of donors 1.03956654822048 bayes_pls_golite062009
nucleic acid binding 0.868888700854563 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 0.82673050487418 bayes_pls_golite062009
DNA binding 0.790382977752475 bayes_pls_golite062009
binding 0.784517759335365 bayes_pls_golite062009
transcription regulator activity 0.613310508772122 bayes_pls_golite062009
transcription factor activity 0.11102650759187 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [340-631]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YGGKGYVGQE LQHVLNDRHI PYVLATKKVG FDSDEEVERE LALLGVTHVI CVTGRTHGPG  60
   61 CNTIEYLEGR ADKVFINVRD NMYSATILAH MCRKLGLHYT YIGTGYMFAY DKEHPIGGAE 120
  121 FKEEDEPTFF GSAYSVVKGF TDRQMNYFNQ NGWENLNVRI TLPLSLDLEQ PRNLLSKIIK 180
  181 YKELFDIPVS LTILPDCMNA MCNLMEQRSG GTLNLVNPEP ISLYEVVKIY KEIVDETVNP 240
  241 TSIGVETERA QHLLATKGNC ALDTEKLQSL APVLSAKQSL IKHFSEMTSA AK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 41.0
Match: 1bsvA
Description: GDP-4-keto-6-deoxy-d-mannose epimerase/reductase (GDP-fucose synthetase)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
UDP-glucose 4-epimerase activity 2.13934644118967 bayes_pls_golite062009
catalytic activity 1.79741889688267 bayes_pls_golite062009
oxidoreductase activity, acting on CH-OH group of donors 1.03956654822048 bayes_pls_golite062009
nucleic acid binding 0.868888700854563 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 0.82673050487418 bayes_pls_golite062009
DNA binding 0.790382977752475 bayes_pls_golite062009
binding 0.784517759335365 bayes_pls_golite062009
transcription regulator activity 0.613310508772122 bayes_pls_golite062009
transcription factor activity 0.11102650759187 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle