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View Structure Prediction Details

Protein: add-2
Organism: Caenorhabditis elegans
Length: 611 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for add-2.

Description E-value Query
Range
Subject
Range
gi|187021082, gi... - gi|39592149|emb|CAE75369.1| Hypothetical protein CBG23353 [Caenorhabditis briggsae], gi|187021082|em...
gi|157762592 - gi|157762592|ref|XP_001673638.1| Hypothetical protein CBG23353 [Caenorhabditis briggsae AF16]
746.0 [0..1] [608..1]

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Predicted Domain #1
Region A:
Residues: [1-222]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSDGSDDDTN NDGNYCKNVS YNFLIQRLAE VSNRKCLLLP KKKNRVDYIS IMQTAEFYPE  60
   61 LVNSSPPLEP GFTSCEVFVV DKKVDKDTLH LDNFSPYHIG ATRRTLERQH SYFYRVNESG 120
  121 NFVPAIKTNG THILRILVSI LGSCPALNRK IYRMVKIESQ NKNCLPSLIV YTFEPGHEIP 180
  181 KPNAPAILRR QTSDEIQKIL NIPGTSFSQA HSEAVLNRFY DD

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [223-331]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LPIRDEASDQ KRARYSIEST SSTNNQLNEI NSFVVPKFEG RQESEQLFRD VKVEQFEESA  60
   61 EISINNRALS PHIQPSKTSV VNRPNQQNRK FQNYDMFSAG VISTATVPA

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [332-611]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PMFHPHITPI ADLKDDDGYD PEELTQRNKL ASLYRLVDLF RWSQGIYNHI TVRVSTDPDE  60
   61 ILINAFGQLY SEVSASSLIK VDLDGTVIDG GSTNFGVNQA GYVLHSAIHN GRPEVKCVVH 120
  121 LHHPSVVAVS AQKCGLLPIS QESMIVGDVG YHEYRGILID EAERALLVRD LGDRNVMILR 180
  181 NHGFVVCGES IEHALSLTYH LIIACETQIR TVPGGNTDNV HFPAQSAIKQ VYKVASQGGG 240
  241 GVNRQNGHVN SMQWKKGELE WQAYMRQLDA QGYVTGNVPN 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 46.522879
Match: 1jdiA
Description: L-ribulose-5-phosphate 4-epimerase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 1.58067730905989 bayes_pls_golite062009
binding 1.02928844080554 bayes_pls_golite062009
protein binding 0.424505568216234 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle