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View Structure Prediction Details

Protein: CE04749
Organism: Caenorhabditis elegans
Length: 410 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE04749.

Description E-value Query
Range
Subject
Range
gi|68389578 - gi|68389578|ref|XP_709925.1| PREDICTED: similar to Ctsd protein isoform 6 [Danio rerio]
332.0 [0..17] [407..6]

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Predicted Domain #1
Region A:
Residues: [1-410]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKVEVCSVEN DRGLSRFFGF YVISSKHERI NRRAGCLEII LSSIMIKTIL LLAFVASTSA  60
   61 FVIPFKVHAA VTNITKGGQT LEQTSTFFVA NLTMGTPGQL FTVVIDTSTA DIVIPDMSCK 120
  121 TANNCYNKRR FNQAKSSSYY AYGNKYTYKN NLGTFQGFDA KDTVVIGDRK TDLITIPGVK 180
  181 FMQATDLGLL MDGLGADGIL GLGFTASSQI GGNSPFVQGV NAGDISGTFY SIWLEHFNQT 240
  241 DDLGTHGVIY YGGFDPVHCA PNPTYVPLAS AYAYQLTMSS FKVVGSSATN SNNKYIQTYL 300
  301 DTTTAQIGLP KTYISQVFDS LGISTNVMNA IYPTIVPCNT KITLTFGFVS GTTVSITERD 360
  361 LVISFFGTCR LQIIPTTDRI ILGLPLYRGR CTYFDPIMQR VGFTPALLQD 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 85.154902
Match: 2psgA
Description: REFINED STRUCTURE OF PORCINE PEPSINOGEN AT 1.8 ANGSTROMS RESOLUTION
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
aspartic-type endopeptidase activity 7.9145950161796 bayes_pls_golite062009
aspartic-type peptidase activity 7.9145950161796 bayes_pls_golite062009
peptidase activity 5.78181196721293 bayes_pls_golite062009
endopeptidase activity 5.4888481808613 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 5.39972232367526 bayes_pls_golite062009
hydrolase activity 2.9018128742867 bayes_pls_golite062009
catalytic activity 1.54514410489082 bayes_pls_golite062009
binding 1.10054369202721 bayes_pls_golite062009
receptor binding 0.561225023505917 bayes_pls_golite062009
protein binding 0.193907750061394 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle