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View Structure Prediction Details

Protein: rpa-1
Organism: Caenorhabditis elegans
Length: 655 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for rpa-1.

Description E-value Query
Range
Subject
Range
gi|115496244, gi... - gi|115496244|ref|NP_001068644.1| replication protein A1, 70kDa [Bos taurus], gi|111308484|gb|AAI1998...
531.0 [0..22] [652..5]

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Predicted Domain #1
Region A:
Residues: [1-216]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAAIHINHDV FNKYHTNGKL RLTTGYVQEA IENNGYPGHD GIVQVLKGKV EQGEQLGHAF  60
   61 TFRIRISDGV FQYNALMSAD IDDQIKREVE HLVEGTIIAL TKFEIYDQGE GAKNCFLIKG 120
  121 YKILSRYHQV LTSPEVKPRS HSGKPDEHKG YRPNIIIEDV WPEAEGMAAD YQENMANPPA 180
  181 AKAPKREFGE EASYNRAAAP EATRARAVPP PARRTA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 29.39794
Match: 2b29A
Description: N-terminal domain of the RPA70 subunit of human replication protein A.
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.05826047136716 bayes_pls_golite062009
nucleic acid binding 0.359779538637606 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [217-470]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SNTERGVMPI AMVTPYVSNF KIHGMVSRKE EIRTFPAKNT KVFNFEITDS NGDTIRCTAF  60
   61 NEVAESLYTT ITENLSYYLS GGSVKQANKK FNNTGHDYEI TLRSDSIIEA GGELLAAPKL 120
  121 ILKRVKLGEI AGYAGQLIDV LVVVEKMDPE ATEFTSKAGK SLIKREMELI DESGALVRLT 180
  181 LWGDEATKAL VDDYVQKVIA FKGVIPREFN GGFSLGTGSA TRIISVPEIA GVSELYDWYA 240
  241 NVKPTTEVKM MSQA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 55.0
Match: 1jmcA
Description: Replication protein A 70 KDa subunit (RPA70)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.05826047136716 bayes_pls_golite062009
nucleic acid binding 0.359779538637606 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [471-655]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AGGSNEAPRT IAGLQEMQFG KDSDKGDYAT VKAMITRVNP TNALYRGCAS EGCQKKLVGE  60
   61 NGDYRCEKCN KNMNKFKWLY MMQFELSDET GQVYVTAFGD SAAKIVGKSA AELGELHDES 120
  121 PDEYNAIFER LQFVPKMWRL RCKMDSYNEE VRQKMTVYGV DDVNQDKYIE NLKQMIEQMQ 180
  181 QMSDY

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 46.0
Match: 1l1oC
Description: Replication protein A 70 KDa subunit (RPA70)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.05826047136716 bayes_pls_golite062009
nucleic acid binding 0.359779538637606 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle