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View Structure Prediction Details

Protein: cap-1
Organism: Caenorhabditis elegans
Length: 282 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for cap-1.

Description E-value Query
Range		 Subject
Range
CAZA1_RAT - F-actin-capping protein subunit alpha-1 OS=Rattus norvegicus GN=Capza1 PE=1 SV=1
 451.0 [0..4] [282..8]
CAZA1_BOVIN - F-actin-capping protein subunit alpha-1 OS=Bos taurus GN=CAPZA1 PE=2 SV=1
 450.0 [0..4] [282..8]
gi|61371588, gi|... - gi|61371588|gb|AAX43695.1| capping protein muscle Z-line alpha 1 [synthetic construct], gi|61365542|...
 450.0 [0..4] [282..8]
CAZA1_CHICK - F-actin-capping protein subunit alpha-1 OS=Gallus gallus GN=CAPZA1 PE=1 SV=1
 449.0 [0..4] [282..8]
CAPZA1 - capping protein (actin filament) muscle Z-line, alpha 1
gi|123979702, gi... - gi|61355548|gb|AAX41151.1| capping protein muscle Z-line alpha 1 [synthetic construct], gi|60821852|...
 449.0 [0..4] [282..8]
gi|73981496 - gi|73981496|ref|XP_533066.2| PREDICTED: similar to capping protein (actin filament) muscle Z-line, a...
 449.0 [0..4] [282..8]
gi|109013601 - gi|109013601|ref|XP_001107677.1| PREDICTED: F-actin capping protein alpha-1 subunit [Macaca mulatta]
 449.0 [0..4] [282..8]
CAZA1_MOUSE - F-actin-capping protein subunit alpha-1 OS=Mus musculus GN=Capza1 PE=1 SV=4
 447.0 [0..4] [282..8]
CAZA1_PONAB - F-actin-capping protein subunit alpha-1 OS=Pongo abelii GN=CAPZA1 PE=2 SV=3
CAZA1_PONPY - F-actin-capping protein subunit alpha-1 - Pongo pygmaeus (Orangutan)
 446.0 [0..4] [282..8]

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Predicted Domain #1
Region A:
Residues: [1-282] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSEISDAEKV RIASDFIKHA PPGEFNEVFN SVRMLLENDD LLKNKCVNAI AQYNVGQFVP  60
   61 VKLDGVAKQT LITPYNDLGN GRFYDEVSKK SFKYDHVRKE AADLQPHPAE SGITEQWRQA 120
  121 LQTQLDIYID DHYAKSGTGV VFARNGVFTI CIESHQFQPK NFCNGRWRSE WNVPVGDGKS 180
  181 GSQEMKGKIL SQVHYYEDGN VQLFSEKEPV LKVNVSADFD KTAKEIIHAI SEEETIYQNA 240
  241 VQENYANMSD TTFKALRRQL PVTRAKMDWN KAQTYRIGQE MK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 127.0
Match: 1iznA
Description: Capz alpha-1 subunit
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
actin binding 6.56144513012007 bayes_pls_golite062009
actin filament binding 5.39928513902709 bayes_pls_golite062009
cytoskeletal protein binding 5.10504476256679 bayes_pls_golite062009
binding 2.03345990933192 bayes_pls_golite062009
protein binding 1.31870344025745 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle