YRC Public Data Repository - Protein Structure Prediction

Protein:	cks-1
Organism:	Caenorhabditis elegans
Length:	94 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for cks-1.

Description	E-value	Query Range	Subject Range
CKS1_CAEBR - Cyclin-dependent kinases regulatory subunit OS=Caenorhabditis briggsae GN=cks-1 PE=3 SV=1 gi\|157772581 - gi\|157772581\|ref\|XP_001664355.1\| hypothetical protein CBG15632 [Caenorhabditis briggsae AF16]	171.0	[0..1]	[94..1]
gi\|109505505 - gi\|109505505\|ref\|XP_001054024.1\| PREDICTED: similar to CDC28 protein kinase regulatory subunit 2 [Ra...	152.0	[0..4]	[81..100]
gi\|30585357, gi\|... - gi\|60653171\|gb\|AAX29280.1\| CDC28 protein kinase regulatory subunit 1B [synthetic construct], gi\|6065...	148.0	[0..4]	[81..2]
tr\|G1TB47\|G1TB47... - pep:novel chromosome:oryCun2:13:37687026:37690344:-1 gene:ENSOCUG00000016204 transcript:ENSOCUT00000... gi\|197245984, gi... - gi\|209364532\|ref\|NP_001129221.1\| RGD1561797 [Rattus norvegicus], gi\|197245984\|gb\|AAI68780.1\| RGD1561... gi\|149751352 - gi\|149751352\|ref\|XP_001497802.1\| PREDICTED: similar to Cks1 protein homologue [Equus caballus] ENSCJAT00000018072 - null gi\|109017139, gi... - gi\|109017141\|ref\|XP_001114905.1\| PREDICTED: similar to Cyclin-dependent kinases regulatory subunit 1... CCDS1077.1_1 - null gi\|194036102 - gi\|194036102\|ref\|XP_001929406.1\| PREDICTED: similar to CDC28 protein kinase 1B [Sus scrofa] CKS1_MOUSE - Cyclin-dependent kinases regulatory subunit 1 OS=Mus musculus GN=Cks1b PE=3 SV=1 CKS1B - CDC28 protein kinase regulatory subunit 1B gi\|123994417, gi... - gi\|60656225\|gb\|AAX32676.1\| CDC28 protein kinase regulatory subunit 1B [synthetic construct], gi\|6065... gi\|73961622 - gi\|73961622\|ref\|XP_855067.1\| PREDICTED: similar to Cyclin-dependent kinases regulatory subunit 1 (CK... CKS1_BOVIN - Cyclin-dependent kinases regulatory subunit 1 OS=Bos taurus GN=CKS1B PE=3 SV=1 ENSPTRT00000002560 - null	147.0	[0..4]	[81..2]
gi\|12847359 - gi\|12847359\|dbj\|BAB27540.1\| unnamed protein product [Mus musculus]	147.0	[0..4]	[81..2]
gi\|109009542 - gi\|109009542\|ref\|XP_001109081.1\| PREDICTED: similar to Cyclin-dependent kinases regulatory subunit 1...	145.0	[0..4]	[81..2]
gi\|213625418, gi... - gi\|62859187\|ref\|NP_001016170.1\| CDC28 protein kinase regulatory subunit 2 [Xenopus (Silurana) tropic...	144.0	[0..6]	[81..4]

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Predicted Domain #1

Region A:
Residues: [1-94]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTTGNNDFYY SNKYEDDEFE YRHVHVTKDV SKLIPKNRLM SETEWRSLGI QQSPGWMHYM  60
   61 IHGPERHVLL FRRPLAATQK TGGNVRSGNA VGVR

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	36.221849
Match:	1buhB
Description:	CksHs1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
cyclin-dependent protein kinase regulator activity	3.97841828100668	bayes_pls_golite062009
binding	2.18113207610794	bayes_pls_golite062009
protein binding	1.97943309243131	bayes_pls_golite062009
protein kinase regulator activity	1.37860707665544	bayes_pls_golite062009
kinase regulator activity	1.32978090173102	bayes_pls_golite062009
protein kinase binding	0.944579171364175	bayes_pls_golite062009
kinase binding	0.867010292327918	bayes_pls_golite062009
ubiquitin binding	0.417755994450789	bayes_pls_golite062009
enzyme binding	0.349317458622834	bayes_pls_golite062009
enzyme regulator activity	0.334428481657021	bayes_pls_golite062009
small conjugating protein binding	0.32298430897304	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: