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View Structure Prediction Details

Protein: tag-320
Organism: Caenorhabditis elegans
Length: 440 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for tag-320.

Description E-value Query
Range
Subject
Range
gi|76630218 - gi|76630218|ref|XP_879722.1| PREDICTED: similar to Protein disulfide-isomerase A6 precursor (Thiored...
368.0 [0..1] [437..1]

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Predicted Domain #1
Region A:
Residues: [1-137]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MALIKLLLAS LAITSVCGMY SKKDDVVELT EANFQSKVIN SDDIWIVEFY APWCGHCKSL  60
   61 VPEYKKAASA LKGVAKVGAV DMTQHQSVGG PYNVQGFPTL KIFGADKKKP TDYNGQRTAQ 120
  121 AIADSVLAEA KKAVSAR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 30.522879
Match: 2dmlA
Description: No description for 2dmlA was found.

Predicted Domain #2
Region A:
Residues: [138-277]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LGGKSSGSSS SGSGSGSGKR GGGGSGNEVV ELTDANFEDL VLNSKDIWLV EFFAPWCGHC  60
   61 KSLEPQWKAA ASELKGKVRL GALDATVHTV VANKFAIRGF PTIKYFAPGS DVSDAQDYDG 120
  121 GRQSSDIVAW ASARAQENMP 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 26.522879
Match: 1x5dA
Description: The solution structure of the second thioredoxin-like domain of human Protein disulfide-isomerase A6
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [278-440]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 APEVFEGINQ QVVEDACKEK QLCIFAFLPH ILDCQSECRN NYLAMLKEQS EKFKKNLWGW  60
   61 IWVEGAAQPA LEESFEVGGF GYPAMTALNF RKNKYAVLKG SFGKDGIHEF LRDLSYGKGR 120
  121 TSSLRGDGFP KIQKTEKWDG KDGALPAEDD IDLSDIDLDK TEL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 13.221849
Match: 2djkA
Description: No description for 2djkA was found.

Predicted functions:

Term Confidence Notes
protein disulfide isomerase activity 4.54149370439152 bayes_pls_golite062009
intramolecular oxidoreductase activity, transposing S-S bonds 4.54149370439152 bayes_pls_golite062009
intramolecular oxidoreductase activity, interconverting keto- and enol-groups 4.32416700334664 bayes_pls_golite062009
disulfide oxidoreductase activity 1.07184913651636 bayes_pls_golite062009
oxidoreductase activity, acting on sulfur group of donors 0.858243161645005 bayes_pls_golite062009
catalytic activity 0.672192331361968 bayes_pls_golite062009
protein disulfide oxidoreductase activity 0.44918717550973 bayes_pls_golite062009
binding 0.235855919597681 bayes_pls_golite062009
protein binding 0.157273259994554 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle