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View Structure Prediction Details

Protein: prx-5
Organism: Caenorhabditis elegans
Length: 502 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for prx-5.

Description E-value Query
Range
Subject
Range
gi|56967372, gi|... - gi|62821820|ref|NP_001017359.1| O-linked N-acetylglucosamine transferase isoform 1 [Danio rerio], gi...
324.0 [0..49] [499..27]

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Predicted Domain #1
Region A:
Residues: [1-154]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKGVVEGQCG QQNALVGLAN TFGTSNQRVA PSNAAASLLP SSSMGEQMAN EFLRQQARTM  60
   61 APTSFSMKSM QNNLPQASAS SSLAANWTKE FQPRQNQLAS QWSQQYTSSA PSMESAWRQV 120
  121 QAPSMTSTSS HQPITDAGMW SSEYLDTVDT SLTK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 12.0
Match: 1xnfA
Description: Crystal structure of E.coli TPR-protein NlpI
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [155-502]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSGTQNWADD FMEQQDNYGM ENTWKDAQAF EQRWEEIKRD MEKDESLQSP ENYVYQEANP  60
   61 FTTMSDPLME GDNLMRNGDI GNAMLAYEAA VQKDPQDARA WCKLGLAHAE NEKDQLAMQA 120
  121 FQKCLQIDAG NKEALLGLSV SQANEGMENE ALHQLDKWMS SYLGSNSTQV TTTPPLYSSF 180
  181 LDSDTFNRVE ARFLDAARQQ GATPDPDLQN ALGVLYNLNR NFARAVDSLK LAISKNPTDA 240
  241 RLWNRLGATL ANGDHTAEAI SAYREALKLY PTYVRARYNL GISCMQLSSY DEALKHFLSA 300
  301 LELQKGGNDA SGIWTTMRSA AIRTSNVPDN LLRAVERRDL AAVKASLV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 31.30103
Match: 1fchA
Description: Peroxin pex5 (peroxisomal targeting signal 1 (PTS1) receptor)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
peroxisome targeting sequence binding 6.28836842401449 bayes_pls_golite062009
peroxisome matrix targeting signal-1 binding 5.30441166392789 bayes_pls_golite062009
binding 2.09193012129784 bayes_pls_golite062009
protein binding 1.52807685989528 bayes_pls_golite062009
signal sequence binding 1.13935627118933 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle