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View Structure Prediction Details

Protein: CE02998
Organism: Caenorhabditis elegans
Length: 459 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE02998.

Description E-value Query
Range
Subject
Range
gi|23092863, gi|... - gi|24656434|ref|NP_647768.2| CG1869-PA [Drosophila melanogaster], gi|23092863|gb|AAF47714.2| CG1869-...
351.0 [0..86] [448..106]

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Predicted Domain #1
Region A:
Residues: [1-98]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPSENITPRV NDLLLENRDN RRRNGNALST KTITYSISIL VVILIMAIPI AYTLSEIVMY  60
   61 AYRNNETASK YIGIIINSIN VRALHAPKKA EDVDQPPS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [99-459]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AKCNKRIVGY YTDWEPRKIS AKQLQKLTHL IFTNVPMNSS GHVFFENLAQ RRRFLEINRK  60
   61 AQLMNVKVMF SIGGHKNAEH YSTVVADSTK RSVFIDSIVS FIKSNNASGV DLFWEWPNIS 120
  121 EMNDFITTIK ELRKKLAALT KAQPKGTRYL LSIIVPSSPS DLEYYLRMDG LLHYVDFLNV 180
  181 LTYGYYAPWS GVNGKFVGPN APLYGGNREN VDETMQYLIC KTRTPSKLNM ALSFYGRYWE 240
  241 NVNDNVPDEM FKEADLINGK AQGMFVAWKN LAGRGWDKSE ALWHEETQIP YIWNSEERKF 300
  301 FVFENERSLQ AKMDYAADHN IGGVYIWALG ADDNNDTLLN VVSSADLCEG GSGNTLISLC 360
  361 G

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 88.045757
Match: 1wawA
Description: Specificity and affnity of natural product cyclopentapeptide inhibitor Argadin against human chitinase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
growth factor activity 2.82687310390294 bayes_pls_golite062009
receptor binding 1.60923678333208 bayes_pls_golite062009
binding 1.07141933768756 bayes_pls_golite062009
carbohydrate binding 0.80333288291596 bayes_pls_golite062009
protein binding 0.41522498233974 bayes_pls_golite062009
hydrolase activity, acting on glycosyl bonds 0.141107738097631 bayes_pls_golite062009
pattern binding 0.113396113487931 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle