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View Structure Prediction Details

Protein: unc-115
Organism: Caenorhabditis elegans
Length: 639 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for unc-115.

Description E-value Query
Range
Subject
Range
gi|76651068 - gi|76651068|ref|XP_887912.1| PREDICTED: similar to zinc finger protein 192 isoform 5 [Bos taurus]
531.0 [0..2] [482..358]

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Predicted Domain #1
Region A:
Residues: [1-194]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKFSRPVLSV NHLILGKKCD VCRKKCSGDV LKANDKYFHI NCFQCKKCGR NLGETGFYTT  60
   61 PENAYLCPDD FRAVSKEITV KTTTQQAHAS SSSAATPKSP EKSNGTTDVS SSGAANATLQ 120
  121 QISPLGSPTT CAACDQALHS GQVLLALGLS WHVYCFKCSE CSAVLHGEYM SHHGKPLCLR 180
  181 DYNEKFGVKC YECE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 46.154902
Match: 2i13A
Description: No description for 2i13A was found.

Predicted Domain #2
Region A:
Residues: [195-443]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KFIAGKVLQA GGYKFHPTCA RCSRCGSHFG DGEEMYMQGD EIWHPSCEHA RTTENIAPTG  60
   61 RAATLSRNEP KYQSTFGQHQ AYMYLLPEVE QTYLRHPVMN AKEPNAPQYH VPQGPIKIRK 120
  121 SRMSMLKTGM QRLTEDLEKN IPRPKSPHMD NEEPIELAHY PAAHVPDPDT LPAIEREDFP 180
  181 APQFPYAVEE LKRRLSTSSV ENEISDDEYS ESDKVDEDKL RKTVETLEKY NDSSIAHVIR 240
  241 QNIEDSHKK

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.38
Match: 2dfyX
Description: No description for 2dfyX was found.

Predicted Domain #3
Region A:
Residues: [444-576]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QRLPLHWDPR NASRTPSGKK MPHLKFRYDV PINASPSRHL NRPRPWVVWQ GGERDQGNNT  60
   61 LPCFHIPEDS RANTLRAATL PTEFGQNLSL ENLDTTISSH YSEHSTTESG TAGGPRSAGG 120
  121 AVLRSSLPDM SKP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [577-639]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AKQYDLLFLQ TTNSDLPEDV DRQHLERHLP RDQFEEIFKM SLIEFYKLPE WKRINLKRKH  60
   61 KLF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 29.045757
Match: 1ujsA
Description: Solution structure of the Villin headpiece domain of human actin-binding LIM protein homologue (KIAA0843 protein)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.890394134199723 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle